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Literature summary for 3.5.3.6 extracted from

  • Starikova, E.A.; Sokolov, A.V.; Vlasenko, A.Y.; Burova, L.A.; Freidlin, I.S.; Vasilyev, V.B.
    Biochemical and biological activity of arginine deiminase from Streptococcus pyogenes M22 (2016), Biochem. Cell Biol., 94, 129-137 .
    View publication on PubMed
Search for more literature for 3.5.3.6

Application

Application Comment Organism
medicine the enzyme has potential for the suppression of excessive cell proliferation Streptococcus pyogenes

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.67
-
 L-arginine pH and temperature not specified in the publication Streptococcus pyogenes

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
 SDS-PAGE Streptococcus pyogenes
150000 160000 gel filtration Streptococcus pyogenes

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-arginine + H2O Streptococcus pyogenes
-
 L-citrulline + NH3
-
 ?
L-arginine + H2O Streptococcus pyogenes M22
-
 L-citrulline + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Streptococcus pyogenes
-
-
-
Streptococcus pyogenes M22
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine + H2O
-
 Streptococcus pyogenes L-citrulline + NH3
-
 ?
L-arginine + H2O
-
 Streptococcus pyogenes M22 L-citrulline + NH3
-
 ?

Subunits

Subunits Comment Organism
? x * 45000, SDS-PAGE Streptococcus pyogenes

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
35
-
 L-arginine pH and temperature not specified in the publication Streptococcus pyogenes

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8
-
-
 Streptococcus pyogenes

pH Range

pH Minimum pH Maximum Comment Organism
6.4 7.8 pH 6.4: about % of maximal activity, pH 7.8: about % of maximal activity Streptococcus pyogenes