Application | Comment | Organism |
---|---|---|
medicine | arginine deprivation by arginine deiminase I can provide a beneficial strategy for the treatment of pancreatic cancer | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | arginine deiminase formulated with polyethyleneglycol specifically inhibits growth of cell lines lacking argininosuccinate synthetase, inducing caspase activation and induction of apoptosis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
L3.3 cell | - |
Homo sapiens | - |
MiaPaCa-2 cell | - |
Homo sapiens | - |
PANC-1 cell | - |
Homo sapiens | - |
pancreas | - |
Homo sapiens | - |
pancreatic cancer cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Arg + H2O | - |
Homo sapiens | citrulline + NH3 | - |
? | |
additional information | arginine deiminase formulated with polyethyleneglycol specifically inhibits growth of cell lines lacking argininosuccinate synthetase, inducing caspase activation and induction of apoptosis | Homo sapiens | ? | - |
? |