Literature summary for 3.5.3.18 extracted from

Knipp, M.; Braun, O.; Gehrig, P.M.; Sack, R.; Vasak, M.
Zn(II)-free dimethylargininase-1 (DDAH-1) is inhibited upon specific Cys-S-nitrosylation (2003), J. Biol. Chem., 278, 3410-3416.

Inhibitors

Inhibitors	Comment	Organism	Structure
2-(N,N-dimethylamino)-diazenolate-2-oxide	S-nitrosylation of apo-enzyme, holo-enzyme resists, reaction with two of five Cys-residues	Bos taurus
Zn2+	one mol per mol of enzyme, apo-enzyme is active, holoenzyme is activated by removal of Zn2+	Bos taurus

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-

Source Tissue	Comment	Organism	Textmining
brain	-	Bos taurus	-

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Release 2023.1 (January 2023)