Literature summary for 3.5.3.18 extracted from

Birdsey, G.M.; Leiper, J.M.; Vallance, P.
Intramolecular localization of dimethylarginine dimethylaminohydrolase overexpressed in an endothelial cell line (2000), Acta Physiol. Scand., 168, 73-79.

Search for more literature for 3.5.3.18

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	no specific association with organelles or with plasma membrane	Homo sapiens	5829	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
NG,NG-dimethyl-L-arginine + H2O	Homo sapiens	the key role of dimethylarginine dimethylaminohydrolase may be to ensure that under normal conditions the levels of methylarginines are kept low throughout the whole cell	dimethylamine + L-citrulline	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
umbilical vein endothelial cell line	overexpression in the immortalized cell line	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
NG,NG-dimethyl-L-arginine + H2O	-	Homo sapiens	dimethylamine + L-citrulline	-	?
NG,NG-dimethyl-L-arginine + H2O	the key role of dimethylarginine dimethylaminohydrolase may be to ensure that under normal conditions the levels of methylarginines are kept low throughout the whole cell	Homo sapiens	dimethylamine + L-citrulline	-	?

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Release 2023.1 (January 2023)