Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.5.3.15 extracted from

  • Teo, C.Y.; Tejo, B.A.; Leow, A.T.C.; Salleh, A.B.; Abdul Rahman, M.B.
    Novel furan-containing peptide-based inhibitors of protein arginine deiminase type IV (PAD4) (2017), Chem. Biol. Drug Des., 90, 1134-1146 .
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information development of furan-containing inhibitors based on peptide KSIRDTP and molecular docking studies. Inhibitors act reversibly and competitively Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9UM07 isoform Pad4
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
KKSIRDTPA + H2O
-
Homo sapiens KKSI-citrulline-DTPA
-
?
KSIRDTP + H2O
-
Homo sapiens KSI-citrulline-DTP
-
?
N-alpha-benzoyl-L-arginine ethyl ester + H2O
-
Homo sapiens N-alpha-benzoyl-L-citrulline ethyl ester + NH3
-
?
QLSLRTVSL + H2O
-
Homo sapiens QLSL-citrulline-TVSL
-
?
SIRDT + H2O
-
Homo sapiens SI-citrulline-RDT
-
?