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Literature summary for 3.5.3.15 extracted from

  • Choi, M.; Lee, O.H.; Jeon, S.; Park, M.; Lee, D.R.; Ko, J.J.; Yoon, T.K.; Rajkovic, A.; Choi, Y.
    The oocyte-specific transcription factor, Nobox, regulates the expression of Pad6, a peptidylarginine deiminase in the oocyte (2010), FEBS Lett., 584, 3629-3634.
    View publication on PubMed
Search for more literature for 3.5.3.15

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21-pLysS cells Mus musculus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protein L-Arg + H2O Mus musculus
-
 protein L-citrulline + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
the GST-NXHD fusion protein is purified by affinity chromatography Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
oocyte Pad6 mRNA expression is localized to oocytes from primordial through antral follicles, but excluded from granulosa cells, theca cells, and corpora lutea Mus musculus
-
ovary Pad6 mRNA is detected preferentially in adult ovaries Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
protein L-Arg + H2O
-
 Mus musculus protein L-citrulline + NH3
-
 ?

Synonyms

Synonyms Comment Organism
PAD6
-
 Mus musculus
peptidylarginine deiminase 6
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus peptidylarginine deiminase 6 is downregulated in newborn ovary homeobox-null ovaries down