Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.5.3.15 extracted from

  • Abdeen, S.M.; Olusi, S.O.
    Peptidyl arginine deiminase: A novel immunohistochemical marker for liver fibrosis in patients with chronic hepatitis (2010), Acta Histochem., 112, 592-603.
    View publication on PubMed
Search for more literature for 3.5.3.15

Application

Application Comment Organism
medicine peptidyl arginine deiminase is an immunohistochemical marker for liver fibrosis in patients with chronic hepatitis Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protein L-Arg + H2O Homo sapiens
-
 protein-L-citrulline + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte
-
 Homo sapiens
-
liver
-
 Homo sapiens
-
additional information PAD is not detected in gallbladder and appendix Homo sapiens
-
skin
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
protein L-Arg + H2O
-
 Homo sapiens protein-L-citrulline + NH3
-
 ?

Synonyms

Synonyms Comment Organism
PAD
-
 Homo sapiens
peptidyl arginine deiminase
-
 Homo sapiens
peptidylarginine deiminase
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens PAD immunopositivity in the hepatocytes increases with the stage of hepatic fibrosis. PAD immunopositivity by hepatocytes significantly increases with the increase in the CD38 by the hepatic stellate cells. PAD immunopositivity increases with Metavir activity up