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Literature summary for 3.5.3.15 extracted from

  • Esposito, G.; Vitale, A.M.; Leijten, F.P.; Strik, A.M.; Koonen-Reemst, A.M.; Yurttas, P.; Robben, T.J.; Coonrod, S.; Gossen, J.A.
    Peptidylarginine deiminase (PAD) 6 is essential for oocyte cytoskeletal sheet formation and female fertility (2007), Mol. Cell. Endocrinol., 273, 25-31.
    View publication on PubMed
Search for more literature for 3.5.3.15

Protein Variants

Protein Variants Comment Organism
additional information generation of PAD6-deficient mice, enzyme inactivation affects female, but not male, fertility, it results in dispersal of the cytoskeletal sheets in oocytes, phenotype, overview Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol PAD6 Mus musculus 5829
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus PAD 6 is essential for oocyte cytoskeletal sheet formation and female fertility, it plays an important role in germ-cell-specific structures in zygote/embryo development, citrullination is a regulator of fertility, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q8K3V4 PAD6
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Source Tissue

Source Tissue Comment Organism Textmining
embryo PAD6 Mus musculus
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germ cell male and female, unique expression of PAD6 Mus musculus
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oocyte PAD6 Mus musculus
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spermatozoon PPAD6 Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PAD 6 is essential for oocyte cytoskeletal sheet formation and female fertility, it plays an important role in germ-cell-specific structures in zygote/embryo development, citrullination is a regulator of fertility, overview Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
PAD
-
 Mus musculus
peptidylarginine deiminase
-
 Mus musculus