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Literature summary for 3.5.3.15 extracted from

  • Wang, Y.; Wysocka, J.; Sayegh, J.; Lee, Y.H.; Perlin, J.R.; Leonelli, L.; Sonbuchner, L.S.; McDonald, C.H.; Cook, R.G.; Dou, Y.; Roeder, R.G.; Clarke, S.; Stallcup, M.R.; Allis, C.D.; Coonrod, S.A.
    Human PAD4 regulates histone arginine methylation levels via demethylimination (2004), Science, 306, 279-283.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
histone L-arginine + H2O Homo sapiens PAD4 mediates gene expression by regulating Arg methylation and citrullination in histones histone L-citrulline + NH3
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
histone L-arginine + H2O
-
Homo sapiens histone L-citrulline + NH3
-
?
histone L-arginine + H2O PAD4 mediates gene expression by regulating Arg methylation and citrullination in histones Homo sapiens histone L-citrulline + NH3
-
?

Synonyms

Synonyms Comment Organism
PAD4
-
Homo sapiens