Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis. Pressure-induced translational control of PAD2 expression is consistent with a possible role for PAD2 and citrullination in primary open-angle glaucoma | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q08642 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
astrocyte | pressure-treated astrocytes exhibit elevated PAD2 and citrullination without apparent change in PAD2 mRNA | Mus musculus | - |
optic nerve | from older, glaucomatous DBA/2J mice (primary open-angle glaucoma), but not in younger DGB/2J or control C57BL6J mice | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis. Pressure-induced translational control of PAD2 expression is consistent with a possible role for PAD2 and citrullination in primary open-angle glaucoma | Mus musculus | ? | - |
? | |
myelin basic protein L-arginine + H2O | - |
Mus musculus | myelin basic protein L-citrulline + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PAD2 | - |
Mus musculus |