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Literature summary for 3.5.3.15 extracted from
- A novel microtubule independent effect of paclitaxel: the inhibition of peptidylarginine deiminase from bovine brain (1998), Biochim. Biophys. Acta, 1388, 154-160.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| paclitaxel | complete inhibition of amidine hydrolysis of benzoyl-Arg ethyl ester by 12.5 mM, complete inhibition of amidine hydrolysis of myelin basic protein by 0.5 mM, non-competitive | Bos taurus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzoyl-Arg ethyl ester + H2O | - |
Bos taurus | benzoyl-citrulline ethyl ester + NH3 | - |
? | |
| myelin basic protein + H2O | - |
Bos taurus | ? | - |
? | |
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Release 2023.1 (January 2023)
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