Literature summary for 3.5.3.12 extracted from

Griswold, A.R.; Nascimento, M.M.; Burne, R.A.
Distribution, regulation and role of the agmatine deiminase system in mutans streptococci (2009), Oral Microbiol. Immunol., 24, 79-82.

Search for more literature for 3.5.3.12

Activating Compound

Activating Compound	Comment	Organism	Structure
agmatine	-	Streptococcus ratti
agmatine	-	Streptococcus mutans
agmatine	-	Streptococcus sobrinus
agmatine	-	Streptococcus criceti
agmatine	-	Streptococcus downei

Application

Application	Comment	Organism
medicine	remove of dental plaque biofilms	Streptococcus ratti
medicine	remove of dental plaque biofilms	Streptococcus mutans
medicine	remove of dental plaque biofilms	Streptococcus sobrinus
medicine	remove of dental plaque biofilms	Streptococcus criceti
medicine	remove of dental plaque biofilms	Streptococcus downei

Inhibitors

Inhibitors	Comment	Organism	Structure
carbohydrate	-	Streptococcus mutans

Organism

Organism	UniProt	Comment	Textmining
no activity in Streptococcus gordonii	-	-	-
no activity in Streptococcus sanguinis	-	genospecies 1	-
Streptococcus criceti	-	-	-
Streptococcus criceti AHT	-	-	-
Streptococcus downei	-	-	-
Streptococcus downei 33748	-	-	-
Streptococcus mutans	-	strain UA159 and strain GS-5	-
Streptococcus oralis	-	-	-
Streptococcus ratti	-	strain FA-1 and strain BHT	-
Streptococcus salivarius	-	-	-
Streptococcus sanguinis	-	genospecies 2	-
Streptococcus sobrinus	-	-	-
Streptococcus sobrinus 6715	-	-	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.0002	-	strain FA-1, 25 mM glucose, without agmatine	Streptococcus ratti
0.004	-	strain FA-1, 25 mM galactose, without agmatine	Streptococcus ratti
0.006	-	25 mM glucose + 10 mM agmatine	Streptococcus downei
0.0097	-	25 mM sorbitol + 10 mM agmatine	Streptococcus sobrinus
0.0109	-	25 mM sorbitol + 10 mM agmatine	Streptococcus criceti
0.016	-	25 mM glucose + 10 mM agmatine	Streptococcus sobrinus
0.02	-	strain FA-1, 250 mM glucose, without agmatine	Streptococcus ratti
0.03	-	strain FA-1, 250 mM glucose + 10 mM agmatine	Streptococcus ratti
0.032	-	strain FA-1, 25 mM glucose + 10 mM agmatine	Streptococcus ratti
0.034	-	strain FA-1, 25 mM galactose + 10 mM agmatine	Streptococcus ratti
0.04	-	strain FA-1, 250 mM galactose, without agmatine	Streptococcus ratti
0.052	-	strain BHT, 25 mM glucose + 10 mM agmatine	Streptococcus ratti
0.058	-	strain FA-1, 250 mM galactose + 10 mM agmatine	Streptococcus ratti
0.058	-	strain UA159, 25 mM glucose + 10 mM agmatine	Streptococcus mutans
0.078	-	strain GS-5, 25 mM galactose + 10 mM agmatine	Streptococcus mutans
0.102	-	strain FA-1, 25 mM glucose + 10 mM agmatine	Streptococcus ratti
0.17	-	strain UA159, 25 mM sorbitol + 10 mM agmatine	Streptococcus mutans
0.4762	-	strain UA159, 25 mM galactose + 10 mM agmatine	Streptococcus mutans

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
agmatine + H2O	assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid	Streptococcus sanguinis	NH3 + N-carbamoylputrescine	-	?
agmatine + H2O	assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid	Streptococcus ratti	NH3 + N-carbamoylputrescine	-	?
agmatine + H2O	assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid	Streptococcus mutans	NH3 + N-carbamoylputrescine	-	?
agmatine + H2O	assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid	Streptococcus salivarius	NH3 + N-carbamoylputrescine	-	?
agmatine + H2O	assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid	Streptococcus oralis	NH3 + N-carbamoylputrescine	-	?
agmatine + H2O	assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid	Streptococcus sobrinus	NH3 + N-carbamoylputrescine	-	?
agmatine + H2O	assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid	Streptococcus criceti	NH3 + N-carbamoylputrescine	-	?
agmatine + H2O	assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid	Streptococcus downei	NH3 + N-carbamoylputrescine	-	?
agmatine + H2O	assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid	Streptococcus criceti AHT	NH3 + N-carbamoylputrescine	-	?
agmatine + H2O	assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid	Streptococcus sobrinus 6715	NH3 + N-carbamoylputrescine	-	?
agmatine + H2O	assay at pH 6.0, 30 min, reaction terminated by adding 10% trichloracetic acid	Streptococcus downei 33748	NH3 + N-carbamoylputrescine	-	?

Synonyms

Synonyms	Comment	Organism
agmatine deiminase	-	Streptococcus sanguinis
agmatine deiminase	-	Streptococcus ratti
agmatine deiminase	-	Streptococcus mutans
agmatine deiminase	-	Streptococcus salivarius
agmatine deiminase	-	Streptococcus oralis
agmatine deiminase	-	Streptococcus sobrinus
agmatine deiminase	-	Streptococcus criceti
agmatine deiminase	-	Streptococcus downei

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
additional information	-	assay at pH 6.0, 30 min, reaction stopped by 10% trichloroacetic acid	Streptococcus sanguinis
6	-	assay at	Streptococcus ratti
6	-	assay at	Streptococcus mutans
6	-	assay at	Streptococcus salivarius
6	-	assay at	Streptococcus oralis
6	-	assay at	Streptococcus sobrinus
6	-	assay at	Streptococcus criceti
6	-	assay at	Streptococcus downei

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Release 2023.1 (January 2023)