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Literature summary for 3.5.3.12 extracted from
- Regulation and physiologic significance of the agmatine deiminase system of Streptococcus mutans UA159 (2006), J. Bacteriol., 188, 834-841.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli DH10B | Streptococcus mutans |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| agmatine | AgDS-deficient strain is unable to grow in the presence of 20 mM agmatine, suggesting that AgDS converts a growth-inhibitory substance into products that can enhance acid tolerance | Streptococcus mutans |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptococcus mutans | - |
- |
- |
| Streptococcus mutans UA159 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| agmatine + H2O | agmatine deiminase system (AgDS) | Streptococcus mutans | N-carbamoylputrescine + NH3 | - |
? | |
| agmatine + H2O | agmatine deiminase system (AgDS) | Streptococcus mutans UA159 | N-carbamoylputrescine + NH3 | - |
? | |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | 40 | AgD activity 4fold higher in Streptococcus mutans grown at 42°C than at 37°C, stress response pathway of this organism | Streptococcus mutans |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5 | 7 | AgD induction clearly enhanced at low pH values, aguA ca. 3.7fold higher in cells grown at pH 5 than that grown at pH 7, stress response pathway of this organism | Streptococcus mutans |
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