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Literature summary for 3.5.3.11 extracted from

  • Shao, Y.; Li, C.; Zhang, W.; Xu, W.; Duan, X.; Li, Y.; Qiu, Q.; Jin, C.
    Cloning and comparative analysis the proximal promoter activities of arginase and agmatinase genes in Apostichopus japonicus (2016), Dev. Comp. Immunol., 65, 299-308 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
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Apostichopus japonicus

Organism

Organism UniProt Comment Textmining
Apostichopus japonicus A0A146AXJ2
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General Information

General Information Comment Organism
metabolism utilization of L-arginine in Stichopus japonicus is conducted by three enzymes: nitric oxide synthase, arginase and agmatinase. Balance of the production of these three enzymes is regulated by multiple transcription factors, such as CREB, NF-kappaB/Rel and STAT5, as well as their substrate L-arginine. Stimulation of pathogen LPS disrupts this balance and subsequently influences the immune response conducted by NO Apostichopus japonicus