Literature summary for 3.5.3.1 extracted from

Agunloye, O.M.; Oboh, G.; Ademiluyi, A.O.; Ademosun, A.O.; Akindahunsi, A.A.; Oyagbemi, A.A.; Omobowale, T.O.; Ajibade, T.O.; Adedapo, A.A.
Cardio-protective and antioxidant properties of caffeic acid and chlorogenic acid Mechanistic role of angiotensin converting enzyme, cholinesterase and arginase activities in cyclosporine induced hypertensive rats (2019), Biomed. Pharmacother., 109, 450-458 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
caffeic acid	inhibiting arginase activity by caffeic acid and chlorogenic acid might be a possible mechanism by which they exert their cardio-protective effect	Rattus norvegicus
chlorogenic acid	inhibiting arginase activity by caffeic acid and chlorogenic acid might be a possible mechanism by which they exert their cardio-protective effect	Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-arginine + H2O	Rattus norvegicus	-	L-ornithine + urea	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood plasma	-	Rattus norvegicus	-
heart	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-arginine + H2O	-	Rattus norvegicus	L-ornithine + urea	-	?

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Release 2023.1 (January 2023)