Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(-)-epicatechin | (-)-epicatechin leads to a decreased arginase-2 mRNA expression after 24 h of incubation, in contrast a weak basal arginase-1 mRNA expression is not affected | Homo sapiens | |
(-)-epicatechin | (-)-epicatechin leads to a decreased arginase-2 mRNA expression after 24 h of incubation, in contrast a weak basal arginase-1 mRNA expression is not affected | Rattus norvegicus | |
flavanol-rich cocoa | cocoa flavanols lower arginase-2 mRNA expression and activity | Homo sapiens | |
flavanol-rich cocoa | cocoa flavanols lower arginase-2 mRNA expression and activity | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + H2O | Homo sapiens | arginase competes with nitric oxide synthases for L-arginine as the common substrate | L-ornithine + urea | - |
? | |
L-arginine + H2O | Rattus norvegicus | arginase competes with nitric oxide synthases for L-arginine as the common substrate | L-ornithine + urea | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endothelial cell | - |
Homo sapiens | - |
erythrocyte | - |
Homo sapiens | - |
HUVEC cell | - |
Homo sapiens | - |
kidney | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + H2O | arginase competes with nitric oxide synthases for L-arginine as the common substrate | Homo sapiens | L-ornithine + urea | - |
? | |
L-arginine + H2O | arginase competes with nitric oxide synthases for L-arginine as the common substrate | Rattus norvegicus | L-ornithine + urea | - |
? |
Synonyms | Comment | Organism |
---|---|---|
arginase-2 | - |
Homo sapiens |
arginase-2 | - |
Rattus norvegicus |