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Literature summary for 3.5.3.1 extracted from

  • Bivalacqua, T.J.; Burnett, A.L.; Hellstrom, W.J.; Champion, H.C.
    Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: influence of in vivo gene therapy of anti-arginase (2007), Am. J. Physiol. Heart Circ. Physiol., 292, H1340-H1351.
    View publication on PubMed
Search for more literature for 3.5.3.1

Application

Application Comment Organism
medicine overexpression of arginase in the penis contributes to erectile dysfunction Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
2(S)-amino-6-boronohexanoic acid 0.005 mM, selective arginase inhibitor Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38000
-
 SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-arginine + H2O Mus musculus
-
 L-ornithine + urea
-
 ?
L-arginine + H2O Mus musculus B6/129
-
 L-ornithine + urea
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 hybrid B6/129
-
Mus musculus B6/129
-
 hybrid B6/129
-

Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell
-
 Mus musculus
-
penis
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine + H2O
-
 Mus musculus L-ornithine + urea
-
 ?
L-arginine + H2O
-
 Mus musculus B6/129 L-ornithine + urea
-
 ?

Synonyms

Synonyms Comment Organism
arginase I
-
 Mus musculus