Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-valine | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P07824 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hepatocyte | 24h culture, both enzyme and NOS-2 activity depend strongly on extracellular L-arginine concentrations. Competing for L-arginine influx by addition of L-lysine results in 60-70% inhibition of enzyme. Addition of enzyme inhibitor L-valine to cells leads to 80-90% decrease in enzyme activity and 25% increase in NOS-2 activity | Rattus norvegicus | - |