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Literature summary for 3.5.2.5 extracted from
- Allantoin accumulation mediated by allantoinase downregulation and transport by ureide permease 5 confers salt stress tolerance to Arabidopsis plants (2016), Plant Mol. Biol., 91, 581-595 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene ALN, semi-quantitative RT-PCR enzyme expression analysis | Arabidopsis thaliana |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | generation of knockout by T-DNA insertion, knockdown, and stress-inducible mutants for AtALN revealing that allantoin accumulation is essential for salt stress tolerance, phenotypes, overview | Arabidopsis thaliana |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | required | Arabidopsis thaliana |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (S)-allantoin + H2O | Arabidopsis thaliana | - |
allantoate | - |
? | |
| (S)-allantoin + H2O | Arabidopsis thaliana Col-0 | - |
allantoate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | Q94AP0 | - |
- |
| Arabidopsis thaliana Col-0 | Q94AP0 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | the AtALN promoter activity is present in specific plant tissues during plant development and is strongly repressed by salt stress | Arabidopsis thaliana | - |
| root | - |
Arabidopsis thaliana | - |
| seedling | - |
Arabidopsis thaliana | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (S)-allantoin + H2O | - |
Arabidopsis thaliana | allantoate | - |
? | |
| (S)-allantoin + H2O | - |
Arabidopsis thaliana Col-0 | allantoate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ALN | - |
Arabidopsis thaliana |
| aln-1 | - |
Arabidopsis thaliana |
| aln-2 | - |
Arabidopsis thaliana |
| Salk_142607 | - |
Arabidopsis thaliana |
| Salk_146783 | - |
Arabidopsis thaliana |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Arabidopsis thaliana | allantoin accumulation is mediated by allantoinase downregulation. The AtALN promoter activity is present in specific plant tissues during plant development and is strongly repressed by salt stress | down |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | allantoin accumulation is mediated by allantoinase downregulation. Knockout, knockdown, and stress-inducible mutants of AtALN reveal that allantoin accumulation is essential for salt stress tolerance, phenotypes, overview | Arabidopsis thaliana |
| metabolism | expression of genes for allantoin synthesis and degradation are oppositely regulated during salt stress. The AtALN promoter activity is present in specific plant tissues during plant development and is strongly repressed by salt stress. Allantoin transport mediated by ureide permease 5 (AtUPS5) is an important event in salt stress alleviation | Arabidopsis thaliana |
| physiological function | allantoin accumulation is essential for salt stress tolerance. The regulation of the enzyme-encoding gene is mainly responsible for allantoin accumulation observed under salt stress. Possible roles of allantoin as a protectant compound in oxidative events or signaling, overview | Arabidopsis thaliana |
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