Crystallization (Comment) | Organism |
---|---|
crystal structure (PDB ID 2WT9) analysis, and modeling of substrate binding and unbinding, overview | Acinetobacter baumannii |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
nicotinamide + H2O | Acinetobacter baumannii | - |
nicotinate + NH3 | - |
? | |
pyrazinamide + H2O | Acinetobacter baumannii | - |
pyrazinoic acid + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acinetobacter baumannii | B0VA03 | gene pncA | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
nicotinamide + H2O | - |
Acinetobacter baumannii | nicotinate + NH3 | - |
? | |
nicotinamide + H2O | binding structure involving residues A155, C159, and Ile154, and unbinding mechanism, modeling, overview | Acinetobacter baumannii | nicotinate + NH3 | - |
? | |
pyrazinamide + H2O | - |
Acinetobacter baumannii | pyrazinoic acid + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
More | cf. EC 3.5.1.19 | Acinetobacter baumannii |
nicotinamidase/pyrazinamidase | - |
Acinetobacter baumannii |
PncA | - |
Acinetobacter baumannii |
pyrazinamidase | - |
Acinetobacter baumannii |
PZAse | - |
Acinetobacter baumannii |
General Information | Comment | Organism |
---|---|---|
additional information | protein conformational changes after ligand dissociation, molecular dynamics simulation methods are performed to investigate the unbinding process of nicotinamide using the enzyme's crystal structure. PDB ID 2WT9 | Acinetobacter baumannii |