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Literature summary for 3.5.1.88 extracted from

  • Khan, F.A.; Patil, R.H.; Shinde, D.B.; Sangshetti, J.N.
    Design and synthesis of 4-((5-benzylidene-2,4-dioxothiazolidin-3-yl)methyl)biphenyl-2-carbonitrile analogs as bacterial peptide deformylase inhibitors (2016), Chem. Biol. Drug Des., 88, 938-944 .
    View publication on PubMed
Search for more literature for 3.5.1.88

Inhibitors

Inhibitors Comment Organism Structure
4'-([(5Z)-2,4-dioxo-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-3-yl]methyl)[1,1'-biphenyl]-2-carbonitrile
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 Escherichia coli
4'-([(5Z)-5-[(2,4-dimethoxyphenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]methyl)[1,1'-biphenyl]-2-carbonitrile
-
 Escherichia coli
4'-([(5Z)-5-[(2,5-dimethoxyphenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]methyl)[1,1'-biphenyl]-2-carbonitrile
-
 Escherichia coli
4'-([(5Z)-5-[(2,6-dichlorophenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]methyl)[1,1'-biphenyl]-2-carbonitrile
-
 Escherichia coli
4'-([(5Z)-5-[(2-chlorophenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]methyl)[1,1'-biphenyl]-2-carbonitrile
-
 Escherichia coli
4'-([(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]methyl)[1,1'-biphenyl]-2-carbonitrile
-
 Escherichia coli
4'-([(5Z)-5-[(4-chlorophenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]methyl)[1,1'-biphenyl]-2-carbonitrile
-
 Escherichia coli
4'-([(5Z)-5-[(4-fluorophenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]methyl)[1,1'-biphenyl]-2-carbonitrile
-
 Escherichia coli
4'-([(5Z)-5-[(4-methoxyphenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]methyl)[1,1'-biphenyl]-2-carbonitrile
-
 Escherichia coli
4'-[(2-ethyl-6,8-dimethyl-3,5-dihydroimidazo[1,2-b]pyridazin-3-yl)methyl][1,1'-biphenyl]-2-carboxylic acid
-
 Escherichia coli
4'-[[(5Z)-5-benzylidene-2,4-dioxo-1,3-thiazolidin-3-yl]methyl][1,1'-biphenyl]-2-carbonitrile
-
 Escherichia coli
6-chloro-2-propyl-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole
-
 Escherichia coli
additional information design and synthesis of 4-((5-benzylidene-2,4-dioxothiazolidin-3-yl)methyl)biphenyl-2-carbonitrile analogues as bacterial peptide deformylase inhibitors, structure-activity relationship analysis, docking study, detailed overview. Antibacterial activity compared to standard ampicillin, MIC values for Escherichia coli and Bacillus subtilis Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P0A6K3
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Synonyms

Synonyms Comment Organism
PDF
-
 Escherichia coli