Application | Comment | Organism |
---|---|---|
medicine | target of antibiotic drugs | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Co(III)1 | peptide cleaving catalyst | Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | - |
Escherichia coli | |
Zn2+ | - |
Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
formyl-L-methionyl peptide + H2O | Escherichia coli | - |
formate + methionyl peptide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Oxidation Stability | Organism |
---|---|
active peptide deformylase has an Fe2+ ion in the active site, which reacts readily with oxygen. To obtain a stable variant, Fe ist often substituted with Zn. | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
formyl-L-methionyl peptide + H2O | - |
Escherichia coli | formate + methionyl peptide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
- |
Escherichia coli | |
peptide deformylase | - |
Escherichia coli |