Inhibitors | Comment | Organism | Structure |
---|---|---|---|
actinonin | - |
Arabidopsis thaliana | |
actinonin | - |
Escherichia coli | |
imino[(5-methoxy-5-oxo-4-[2-(sulfanylmethyl)hexanoyl]aminopentyl)amino]methaneamine | - |
Arabidopsis thaliana | |
imino[(5-methoxy-5-oxo-4-[2-(sulfanylmethyl)hexanoyl]aminopentyl)amino]methaneamine | - |
Escherichia coli | |
methyl-1-(sulfanylmethyl)hexanoate | - |
Arabidopsis thaliana | |
methyl-1-(sulfanylmethyl)hexanoate | - |
Escherichia coli | |
Phe-Arg-beta-naphthylamide | - |
Arabidopsis thaliana | |
thiorphan | - |
Arabidopsis thaliana |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Arabidopsis thaliana | |
0.23 | - |
N-Formyl-Met-Leu-Phe | enzyme form PDF1A | Arabidopsis thaliana | |
0.25 | - |
N-formyl-Met-Ala-Ser | enzyme form PDF1A | Arabidopsis thaliana | |
0.27 | - |
N-formyl-Met-Ala-Ser | enzyme form PDF1A | Solanum lycopersicum | |
0.42 | - |
N-formyl-Arg(NH2) | enzyme form PDF1A | Arabidopsis thaliana | |
0.42 | - |
N-formyl-Ser(NH2) | enzyme form PDF1A | Arabidopsis thaliana | |
0.5 | - |
N-formyl-L-Arg-amide | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
0.6 | - |
N-formyl-Nle-Ala-Ser | enzyme form PDF1A | Arabidopsis thaliana | |
0.74 | - |
N-formyl-Asp(NH2) | enzyme form PDF1A | Arabidopsis thaliana | |
0.79 | - |
N-formyl-Leu(NH2) | enzyme form PDF1A | Arabidopsis thaliana | |
1 | - |
N-formyl-Asp(NH2) | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
1 | - |
N-formyl-Ser(NH2) | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
2 | - |
N-formyl-Met-Ser-Asn-Glu | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
2.9 | - |
N-formyl-Gly(NH2) | enzyme form PDF1A | Arabidopsis thaliana | |
3 | - |
N-formyl-Phe-Ala-Ser | enzyme form PDF1A | Arabidopsis thaliana | |
4.1 | - |
N-formyl-Met-Ser-Asn-Glu | enzyme form PDF1A | Arabidopsis thaliana | |
4.3 | - |
N-formyl-Gly(NH2) | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
5.6 | - |
N-formyl-Met-Ala-Ser | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
8 | - |
N-formyl-Met-Leu-Glu | enzyme form PDF1A | Arabidopsis thaliana | |
8.2 | - |
N-formyl-Met-Ala-Ser | enzyme form PDF1B | Arabidopsis thaliana | |
9.4 | - |
N-formyl-Nva-Ala-Ser | enzyme form PDF1A | Arabidopsis thaliana | |
11 | - |
N-formyl-Nle-Ala-Ser | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
12 | - |
N-formyl-Met-Leu-Glu | enzyme form Ni-PDF1B | Arabidopsis thaliana |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
chloroplast | - |
Arabidopsis thaliana | 9507 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe | - |
Escherichia coli | |
Fe | PDF1B is an iron enzyme | Arabidopsis thaliana | |
Zn | PDF1A is a zinc enzyme, contains 0.8 mol of Zn per mol of enzyme | Arabidopsis thaliana | |
Zn | PDF1A is a zinc enzyme, contains 0.8 mol of Zn per mol of enzyme | Solanum lycopersicum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-formyl-L-methionine-polypeptide + H2O | Escherichia coli | - |
formate + L-methionine-polypeptide | - |
? | |
N-formyl-L-methionine-polypeptide + H2O | Arabidopsis thaliana | deformylase is likely to play an essential role in the chloroplast | formate + L-methionine-polypeptide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
two classes of PDF: PDF1A and PDF1B | - |
Escherichia coli | - |
- |
- |
Solanum lycopersicum | - |
two classes of PDF: PDF1A and PDF1B | - |
Purification (Comment) | Organism |
---|---|
two classes of PDF: PDF1A and PDF1B | Arabidopsis thaliana |
two classes of PDF: PDF1A and PDF1B | Solanum lycopersicum |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
seedling | - |
Arabidopsis thaliana | - |
Storage Stability | Organism |
---|---|
-20°C, PDF1A is stable for at least 6 months | Arabidopsis thaliana |
-20°C, PDF1A is stable for at least 6 months | Solanum lycopersicum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-formyl-Asp(NH2) + H2O | - |
Arabidopsis thaliana | ? | - |
? | |
N-formyl-Gly(NH2) + H2O | - |
Arabidopsis thaliana | ? | - |
? | |
N-formyl-L-Arg(NH2) + H2O | - |
Arabidopsis thaliana | ? | - |
? | |
N-formyl-L-Arg-amide + H2O | - |
Arabidopsis thaliana | ? | - |
? | |
N-formyl-L-methionine-polypeptide + H2O | - |
Escherichia coli | formate + L-methionine-polypeptide | - |
? | |
N-formyl-L-methionine-polypeptide + H2O | deformylase is likely to play an essential role in the chloroplast | Arabidopsis thaliana | formate + L-methionine-polypeptide | - |
? | |
N-formyl-Leu(NH2) + H2O | - |
Arabidopsis thaliana | ? | - |
? | |
N-formyl-Met-Ala + H2O | - |
Escherichia coli | formate + Met-Ala | - |
? | |
N-formyl-Met-Ala + H2O | - |
Arabidopsis thaliana | formate + Met-Ala | - |
? | |
N-formyl-Met-Ala(OCH3) + H2O | - |
Escherichia coli | formate + Met-Ala(OCH3) | - |
? | |
N-formyl-Met-Ala(OCH3) + H2O | - |
Arabidopsis thaliana | formate + Met-Ala(OCH3) | - |
? | |
N-formyl-Met-Ala-Ser + H2O | - |
Escherichia coli | formate + Met-Ala-Ser | - |
? | |
N-formyl-Met-Ala-Ser + H2O | - |
Arabidopsis thaliana | formate + Met-Ala-Ser | - |
? | |
N-formyl-Met-Ala-Ser + H2O | - |
Solanum lycopersicum | formate + Met-Ala-Ser | - |
? | |
N-formyl-Met-Leu-Glu + H2O | - |
Escherichia coli | formate + Met-Leu-Glu | - |
? | |
N-formyl-Met-Leu-Glu + H2O | - |
Arabidopsis thaliana | formate + Met-Leu-Glu | - |
? | |
N-formyl-Met-Leu-p-nitroanilide + H2O | - |
Escherichia coli | formate + Met-Leu-p-nitroanilide | - |
? | |
N-formyl-Met-Leu-p-nitroanilide + H2O | - |
Arabidopsis thaliana | formate + Met-Leu-p-nitroanilide | - |
? | |
N-formyl-Met-Leu-Phe + H2O | - |
Escherichia coli | formate + Met-Leu-Phe | - |
? | |
N-formyl-Met-Leu-Phe + H2O | - |
Arabidopsis thaliana | formate + Met-Leu-Phe | - |
? | |
N-formyl-Met-Ser-Asn-Glu + H2O | - |
Escherichia coli | formate + Met-Ser-Asn-Glu | - |
? | |
N-formyl-Met-Ser-Asn-Glu + H2O | - |
Arabidopsis thaliana | formate + Met-Ser-Asn-Glu | - |
? | |
N-formyl-Nle-Ala(NH2) + H2O | - |
Escherichia coli | formate + Nle-Ala(NH2) | - |
? | |
N-formyl-Nle-Ala(NH2) + H2O | - |
Arabidopsis thaliana | formate + Nle-Ala(NH2) | - |
? | |
N-formyl-Nle-Ala-Ser + H2O | - |
Escherichia coli | formate + Nle-Ala-Ser | - |
? | |
N-formyl-Nle-Ala-Ser + H2O | - |
Arabidopsis thaliana | formate + Nle-Ala-Ser | - |
? | |
N-formyl-Nle-Arg(NH2) + H2O | - |
Escherichia coli | formate + Nle-Arg(NH2) | - |
? | |
N-formyl-Nle-Arg(NH2) + H2O | - |
Arabidopsis thaliana | formate + Nle-Arg(NH2) | - |
? | |
N-formyl-Nle-Asp(NH2) + H2O | - |
Escherichia coli | formate + Nle-Asp(NH2) | - |
? | |
N-formyl-Nle-Asp(NH2) + H2O | - |
Arabidopsis thaliana | formate + Nle-Asp(NH2) | - |
? | |
N-formyl-Nle-Gly(NH2) + H2O | - |
Escherichia coli | formate + Nle-Gly(NH2) | - |
? | |
N-formyl-Nle-Gly(NH2) + H2O | - |
Arabidopsis thaliana | formate + Nle-Gly(NH2) | - |
? | |
N-formyl-Nle-Leu(NH2) + H2O | - |
Escherichia coli | formate + Nle-Leu(NH2) | - |
? | |
N-formyl-Nle-Leu(NH2) + H2O | - |
Arabidopsis thaliana | formate + Nle-Leu(NH2) | - |
? | |
N-formyl-Nle-NH(CH3) + H2O | - |
Escherichia coli | formate + Nle-NH(CH3) | - |
? | |
N-formyl-Nle-NH(CH3) + H2O | - |
Arabidopsis thaliana | formate + Nle-NH(CH3) | - |
? | |
N-formyl-Nle-NH2 + H2O | - |
Escherichia coli | formate + Nle-Nle-NH2 | - |
? | |
N-formyl-Nle-NH2 + H2O | - |
Arabidopsis thaliana | formate + Nle-Nle-NH2 | - |
? | |
N-formyl-Nle-Ser(NH2) + H2O | - |
Escherichia coli | formate + Nle-Ser(NH2) | - |
? | |
N-formyl-Nle-Ser(NH2) + H2O | - |
Arabidopsis thaliana | formate + Nle-Ser(NH2) | - |
? | |
N-formyl-Nva-Ala-Ser + H2O | - |
Escherichia coli | formate + Nva-Ala-Ser | - |
? | |
N-formyl-Nva-Ala-Ser + H2O | - |
Arabidopsis thaliana | formate + Nva-Ala-Ser | - |
? | |
N-formyl-Phe-Ala-Ser + H2O | - |
Escherichia coli | formate + Phe-Ala-Ser | - |
? | |
N-formyl-Phe-Ala-Ser + H2O | - |
Arabidopsis thaliana | formate + Phe-Ala-Ser | - |
? | |
N-formyl-Ser(NH2) + H2O | - |
Arabidopsis thaliana | ? | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Arabidopsis thaliana | |
0.36 | - |
N-formyl-Nle-Leu(NH2) | enzyme form PDF1A | Arabidopsis thaliana | |
0.4 | - |
N-formyl-Nle-Asp(NH2) | enzyme form PDF1A | Arabidopsis thaliana | |
0.6 | - |
N-formyl-Phe-Ala-Ser | enzyme form PDF1A | Arabidopsis thaliana | |
0.7 | - |
N-Formyl-Met-Leu-Phe | enzyme form PDF1A | Arabidopsis thaliana | |
1.1 | - |
N-formyl-Met-Leu-Glu | enzyme form PDF1A | Arabidopsis thaliana | |
1.4 | - |
N-formyl-Nle-Gly(NH2) | enzyme form PDF1A | Arabidopsis thaliana | |
1.9 | - |
N-formyl-Met-Ser-Asn-Glu | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
5 | - |
N-formyl-Nle-Arg(NH2) | enzyme form PDF1A | Arabidopsis thaliana | |
6.4 | - |
N-formyl-Nle-Asp(NH2) | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
9.2 | - |
N-formyl-Met-Leu-Glu | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
10 | - |
N-formyl-Nle-Ser(NH2) | enzyme form PDF1A | Arabidopsis thaliana | |
11 | - |
N-formyl-Met-Ser-Asn-Glu | enzyme form PDF1A | Arabidopsis thaliana | |
13 | - |
N-formyl-Met-Ala-Ser | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
15 | - |
N-formyl-Met-Ala-Ser | enzyme form PDF1A | Solanum lycopersicum | |
18 | - |
N-formyl-Nva-Ala-Ser | enzyme form PDF1A | Arabidopsis thaliana | |
22 | - |
N-formyl-Met-Ala-Ser | enzyme form PDF1A | Arabidopsis thaliana | |
26 | - |
N-formyl-Nle-Ala-Ser | enzyme form PDF1A | Arabidopsis thaliana | |
51 | - |
N-formyl-Nle-Ser(NH2) | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
75 | - |
N-formyl-Met-Ala-Ser | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
136 | - |
N-formyl-Nle-Ala-Ser | enzyme form Ni-PDF1B | Arabidopsis thaliana | |
138 | - |
N-formyl-Nle-Arg(NH2) | enzyme form Ni-PDF1B | Arabidopsis thaliana |