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Literature summary for 3.5.1.78 extracted from

  • Chen, S.; Lin, C.H.; Kwon, D.S.; Walsh, C.T.; Coward, J.K.
    Design, synthesis, and biochemical evaluation of phosphonate and phosphonamidate analogs of glutathionylspermidine as inhibitors of glutathionylspermidine synthetase/amidase from Escherichia coli (1997), J. Med. Chem., 40, 3842-3850.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Polyamine-containing phosphopeptides potent and selective inhibitors, which selectively inhibit the synthetase domain over the amidase domain Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
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bifunctional enzyme glutathionylspermidine synthetase/amidase
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Purification (Commentary)

Purification (Comment) Organism
-
Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathionylspermidine + H2O
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Escherichia coli glutathione + spermidine
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