Literature summary for 3.5.1.5 extracted from

Sivapriya, K.; Suguna, P.; Banerjee, A.; Saravanan, V.; Rao, D.N.; Chandrasekaran, S.
Facile one-pot synthesis of thio and selenourea derivatives: a new class of potent urease inhibitors (2007), Bioorg. Med. Chem. Lett., 17, 6387-6391.

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Inhibitors

Inhibitors	Comment	Organism	Structure
1,1-dimethyl-3-[(1S)-1-naphthalen-1-ylethyl]selenourea	-	Canavalia ensiformis
1-cyclohexyl-3,3-dimethyl-1-(1-methylethyl)selenourea	-	Canavalia ensiformis
3-(4-bromobenzyl)-1,1-dimethylselenourea	-	Canavalia ensiformis
3-(4-bromophenyl)-1,1-dimethylthiourea	-	Canavalia ensiformis
3-dodecyl-1,1-dimethylthiourea	-	Canavalia ensiformis

Organism

Organism	UniProt	Comment	Textmining
Canavalia ensiformis	-	-	-

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.000025	-	1-cyclohexyl-3,3-dimethyl-1-(1-methylethyl)selenourea	-	Canavalia ensiformis
0.000094	-	1,1-dimethyl-3-[(1S)-1-naphthalen-1-ylethyl]selenourea	-	Canavalia ensiformis
0.000124	-	3-dodecyl-1,1-dimethylthiourea	-	Canavalia ensiformis
0.000135	-	3-(4-bromobenzyl)-1,1-dimethylselenourea	-	Canavalia ensiformis
0.000255	-	3-(4-bromophenyl)-1,1-dimethylthiourea	-	Canavalia ensiformis

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Release 2023.1 (January 2023)