BRENDA - Enzyme Database show
show all sequences of 3.5.1.42

NAD deamidation a new reaction by an enzyme from Aspergillus terreus DSM 826

Elzainy, T.A.; Ali, T.H.; Antonie van Leeuwenhoek 87, 119-129 (2005)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
deamido-NAD+
product inhibition
Aspergillus terreus
Mg2+
-
Aspergillus terreus
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Aspergillus terreus
-
DSM 826
-
Purification (Commentary)
Commentary
Organism
-
Aspergillus terreus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
beta-nicotinamide D-ribonucleotide + H2O
-
663668
Aspergillus terreus
beta-nicotinate D-ribonucleotide + NH3
-
-
-
?
nicotinamide + H2O
-
663668
Aspergillus terreus
nicotinate + NH3
-
-
-
?
nicotinamide mononucleotide + H2O
-
663668
Aspergillus terreus
nicotinate mononucleotide + NH3
-
-
-
?
nicotinamide riboside + H2O
-
663668
Aspergillus terreus
nicotinate riboside + NH3
-
-
-
?
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
50
-
-
Aspergillus terreus
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Aspergillus terreus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
deamido-NAD+
product inhibition
Aspergillus terreus
Mg2+
-
Aspergillus terreus
Purification (Commentary) (protein specific)
Commentary
Organism
-
Aspergillus terreus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
beta-nicotinamide D-ribonucleotide + H2O
-
663668
Aspergillus terreus
beta-nicotinate D-ribonucleotide + NH3
-
-
-
?
nicotinamide + H2O
-
663668
Aspergillus terreus
nicotinate + NH3
-
-
-
?
nicotinamide mononucleotide + H2O
-
663668
Aspergillus terreus
nicotinate mononucleotide + NH3
-
-
-
?
nicotinamide riboside + H2O
-
663668
Aspergillus terreus
nicotinate riboside + NH3
-
-
-
?
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
50
-
-
Aspergillus terreus
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Aspergillus terreus
Other publictions for EC 3.5.1.42
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
733870
Sorci
Characterization of bacterial ...
Escherichia coli
FEBS Lett.
588
1016-1023
2014
-
-
1
-
7
-
1
5
-
-
-
1
-
1
-
-
1
1
-
-
-
-
1
1
1
-
1
4
1
-
-
-
-
-
-
-
-
1
-
-
7
-
-
1
-
5
-
-
-
1
-
-
-
1
-
-
-
-
1
1
1
-
1
4
1
-
-
-
-
2
2
-
4
4
734285
Karuppiah
Structure and mechanism of the ...
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
J. Biol. Chem.
289
33187-33197
2014
-
-
1
1
-
-
-
-
-
-
-
3
-
4
-
-
1
1
-
-
-
-
6
1
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
3
-
-
-
1
-
-
-
-
6
1
1
-
-
-
1
-
-
-
-
2
2
-
-
-
735110
Sanchez-Carron
New insights into the phylogen ...
Oceanobacillus iheyensis, Oceanobacillus iheyensis HTE831
PLoS ONE
8
e82705
2013
-
-
1
-
-
-
-
2
-
-
2
2
-
4
-
-
1
-
-
-
-
-
2
1
1
-
1
1
1
1
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
-
2
2
-
-
-
1
-
-
-
-
2
1
1
-
1
1
1
1
1
-
-
1
1
-
1
1
719984
Galeazzi
Identification of nicotinamide ...
Escherichia coli, Shewanella oneidensis
J. Biol. Chem.
286
40365-40375
2011
-
-
-
-
-
-
1
2
-
1
3
3
-
6
-
-
1
-
-
-
2
-
3
2
-
-
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
1
3
3
-
-
-
1
-
-
2
-
3
2
-
-
-
2
-
1
-
-
-
1
1
-
-
-
663668
Elzainy
NAD deamidation a new reaction ...
Aspergillus terreus
Antonie van Leeuwenhoek
87
119-129
2005
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
1
-
-
-
-
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
209133
Cheng
Isolation of NAD cycle mutants ...
Salmonella enterica subsp. enterica serovar Typhimurium
J. Bacteriol.
177
6711-6717
1995
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
1
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209134
Kuwahara
-
Nicotinamide nucleoside amidas ...
Aspergillus awamori, Aspergillus flavus, Aspergillus niger, Aspergillus oryzae, Aspergillus usamii, Athelia rolfsii, Fusarium oxysporum, Rhizopus oryzae, Trichoderma deliquescens
J. Ferment. Technol.
61
61-66
1983
-
-
-
-
-
1
2
1
-
-
1
9
-
9
-
-
1
-
-
9
1
-
9
-
1
-
-
-
1
1
1
-
-
-
-
-
-
-
-
-
-
1
-
2
-
1
-
-
1
9
-
-
-
1
-
9
1
-
9
-
1
-
-
-
1
1
1
-
-
-
-
-
-
-
209135
Foster
NAD metabolism in Vibrio chole ...
Vibrio cholerae
J. Bacteriol.
149
368-371
1982
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
1
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
171773
Foster
Pyridine nucleotide cycle of S ...
Salmonella enterica subsp. enterica serovar Typhimurium
J. Bacteriol.
145
1002-1009
1981
-
-
-
-
-
-
-
-
-
-
1
2
-
2
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
2
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209136
Hillyard
The pyridine nucleotide cycle. ...
Escherichia coli, Homo sapiens
J. Biol. Chem.
256
8491-8497
1981
-
-
-
-
-
-
-
1
1
-
-
2
-
5
-
-
1
-
-
3
1
-
4
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
2
-
-
-
1
-
3
1
-
4
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
209138
Kinney
Pyridine nucleotide cycle of S ...
Salmonella enterica subsp. enterica serovar Typhimurium
J. Bacteriol.
140
607-611
1979
-
-
-
-
-
-
-
1
-
-
-
1
-
2
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209139
Friedmann
The pyridine nucleotide cycle: ...
Propionibacterium freudenreichii subsp. shermanii
Biochem. Biophys. Res. Commun.
50
54-58
1973
-
-
-
-
-
-
-
1
-
-
-
2
-
1
-
-
1
-
-
1
-
1
3
1
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
2
-
-
-
1
-
1
-
1
3
1
-
-
-
-
1
-
3
-
-
-
-
-
-
-
209140
Imai
Purification and properties of ...
Azotobacter vinelandii, Escherichia coli, no activity in Oryctolagus cuniculus, no activity in Saccharomyces cerevisiae
J. Biochem.
73
139-153
1973
3
-
-
-
-
1
9
1
-
1
1
3
-
5
-
-
1
-
-
2
1
1
4
-
1
-
1
-
1
-
-
-
7
-
-
3
-
-
-
-
-
1
-
9
7
1
-
1
1
3
-
-
-
1
-
2
1
1
4
-
1
-
1
-
1
-
-
-
-
-
-
-
-
-
209141
Friedmann
-
Preparation of nicotinic acid ...
Propionibacterium freudenreichii subsp. shermanii
Methods Enzymol.
18
192-197
1971
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-