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Literature summary for 3.5.1.41 extracted from

  • Wang, S.; Jayaram, S.A.; Hemphaelae, J.; Senti, K.A.; Tsarouhas, V.; Jin, H.; Samakovlis, C.
    Septate-junction-dependent luminal deposition of chitin deacetylases restricts tube elongation in the Drosophila trachea (2006), Curr. Biol., 16, 180-185.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
overexpression of full-length and truncated enzyme versions as GFP-tagged proteins in recombinant embryos, overview Drosophila melanogaster

Protein Variants

Protein Variants Comment Organism
additional information overexpression of the native, but not of mutated, enzyme interferes with the structural integrity of the intraluminal extracellular matrix and causes aberrant tube elongation, phenotype, overview Drosophila melanogaster

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information dynamic localization, overview Drosophila melanogaster
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Drosophila melanogaster the enzyme has a function in assembly of intraluminal chitinous filament, septate-junction-dependent luminal deposition of the enzyme restricts tube elongation in the trachea, tubular function is critically dependent on the length and diameter of their constituting branches in tubular organs such as kidney, products of genes verm and serp are required, molecular mechanisms, overview ?
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Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
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Source Tissue

Source Tissue Comment Organism Textmining
embryo
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Drosophila melanogaster
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epidermis
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Drosophila melanogaster
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additional information dynamic localization, overview Drosophila melanogaster
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme has a function in assembly of intraluminal chitinous filament, septate-junction-dependent luminal deposition of the enzyme restricts tube elongation in the trachea, tubular function is critically dependent on the length and diameter of their constituting branches in tubular organs such as kidney, products of genes verm and serp are required, molecular mechanisms, overview Drosophila melanogaster ?
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?

Synonyms

Synonyms Comment Organism
ChlD
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Drosophila melanogaster
More the enzyme belongs to the chitin deacetylase feamily Drosophila melanogaster