Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-arachidin | 10% inhibition at 0.1 mM | Rattus norvegicus | |
1-arachidonoylglycerol | IC50: 0.0062 mM | Rattus norvegicus | |
1-myristin | IC50: 0.018, complete inhibition is possible | Rattus norvegicus | |
1-palmitin | IC50: 0.0080, complete inhibition is possible | Rattus norvegicus | |
2,3-dihydroxypropyl (11Z)-icos-11-enoate | i.e. O-4066, IC50: 0.010, complete inhibition is possible | Rattus norvegicus | |
2,3-dihydroxypropyl (11Z,14Z)-icosa-11,14-dienoate | i.e. O-3907, IC50: 0.0057, complete inhibition is possible | Rattus norvegicus | |
2,3-dihydroxypropyl (4Z,7Z,10Z,13Z)-17-ethylcycloheptadeca-4,7,10,13-tetraene-1-carboxylate | i.e. O-1428, 28% inhibition at 0.1 mM | Rattus norvegicus | |
2,3-dihydroxypropyl (5Z)-icos-5-enoate | i.e. 3908, IC50: 0.011, 84% inhibition is possible | Rattus norvegicus | |
2,3-dihydroxypropyl (5Z,8Z,11Z)-2-ethylcycloheptadeca-5,8,11-triene-1-carboxylate | i.e. O-3973, IC50: 0.0024, 95% inhibition is possible | Rattus norvegicus | |
2,3-dihydroxypropyl (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate | i.e. O-3832, IC50: 0.0076, complete inhibition is possible | Rattus norvegicus | |
2,3-dihydroxypropyl (6Z,9Z,12Z,15Z)-cyclohenicosa-6,9,12,15-tetraene-1-carboxylate | i.e. O-4081, IC50: 0.0051, 90% inhibition is possible | Rattus norvegicus | |
2,3-dihydroxypropyl (7Z,10Z,13Z,16Z)-docosa-7,10,13,16-tetraenoate | i.e. O-3872, IC50: 0.014, complete inhibition is possible | Rattus norvegicus | |
2,3-dihydroxypropyl (8Z,11Z,14Z)-icosa-8,11,14-trienoate | i.e. 3846, IC50: 0.023, complete inhibition is possible | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Sprague-Dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
anandamide + H2O | i.e. arachidonoylethanolamide | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FAAH | - |
Rattus norvegicus |
fatty acid amide hydrolase | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
assay at | Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0024 | - |
i.e. O-3973, IC50: 0.0024, 95% inhibition is possible | Rattus norvegicus | 2,3-dihydroxypropyl (5Z,8Z,11Z)-2-ethylcycloheptadeca-5,8,11-triene-1-carboxylate | |
0.0051 | - |
i.e. O-4081, IC50: 0.0051 mM, 90% inhibition is possible | Rattus norvegicus | 2,3-dihydroxypropyl (6Z,9Z,12Z,15Z)-cyclohenicosa-6,9,12,15-tetraene-1-carboxylate | |
0.0057 | - |
i.e. O-3907, IC50: 0.0057 mM, complete inhibition is possible | Rattus norvegicus | 2,3-dihydroxypropyl (11Z,14Z)-icosa-11,14-dienoate | |
0.0062 | - |
IC50: 0.0062 mM | Rattus norvegicus | 1-arachidonoylglycerol | |
0.0076 | - |
i.e. O-3832, IC50: 0.0076 mM, complete inhibition is possible | Rattus norvegicus | 2,3-dihydroxypropyl (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate | |
0.008 | - |
IC50: 0.0080 mM, complete inhibition is possible | Rattus norvegicus | 1-palmitin | |
0.01 | - |
i.e. O-4066, IC50: 0.010 mM, complete inhibition is possible | Rattus norvegicus | 2,3-dihydroxypropyl (11Z)-icos-11-enoate | |
0.011 | - |
i.e. O-3908, IC50: 0.011 mM, 84% inhibition is possible | Rattus norvegicus | 2,3-dihydroxypropyl (5Z)-icos-5-enoate | |
0.014 | - |
i.e. O-3872, IC50: 0.014, complete inhibition is possible | Rattus norvegicus | 2,3-dihydroxypropyl (7Z,10Z,13Z,16Z)-docosa-7,10,13,16-tetraenoate | |
0.018 | - |
IC50: 0.018 mM, complete inhibition is possible | Rattus norvegicus | 1-myristin | |
0.023 | - |
i.e. 3846, IC50: 0.023, complete inhibition is possible | Rattus norvegicus | 2,3-dihydroxypropyl (8Z,11Z,14Z)-icosa-8,11,14-trienoate |