BRENDA - Enzyme Database
show all sequences of 3.5.1.31

N-Formyl-methionine deformylase of animal tissues

Grisolia, S.; Reglero.A.; Rivas, J.; Biochem. Biophys. Res. Commun. 77, 237-244 (1977) View publication on PubMed

Data extracted from this reference:

KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.3
-
N-formyl-methionine
enzyme from spleen
Rattus norvegicus
5
-
N-formyl-methionine
enzyme from brain, heart or muscle
Rattus norvegicus
6.5
-
N-formyl-methionine
enzyme from kidney
Rattus norvegicus
12.5
-
N-formyl-methionine
enzyme from liver
Rattus norvegicus
Organism
Organism
UniProt
Commentary
Textmining
Bos taurus
-
-
-
Gallus gallus
-
-
-
Rattus norvegicus
-
-
-
Sus scrofa
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
brain
-
Rattus norvegicus
-
brain
-
Bos taurus
-
heart
-
Rattus norvegicus
-
kidney
-
Rattus norvegicus
-
kidney
-
Sus scrofa
-
liver
-
Gallus gallus
-
liver
-
Rattus norvegicus
-
muscle
-
Rattus norvegicus
-
spleen
-
Rattus norvegicus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
N-formyl-alanine + H2O
at 2-7% of the activity with N-formyl-methionine, depending on tissue
393796
Rattus norvegicus
formate + alanine
-
-
-
?
N-formyl-L-methionine + H2O
-
393796
Gallus gallus
formate + L-methionine
-
393796
Gallus gallus
?
N-formyl-L-methionine + H2O
-
393796
Rattus norvegicus
formate + L-methionine
-
393796
Rattus norvegicus
?
N-formyl-L-methionine + H2O
-
393796
Sus scrofa
formate + L-methionine
-
393796
Sus scrofa
?
N-formyl-L-methionine + H2O
-
393796
Bos taurus
formate + L-methionine
-
393796
Bos taurus
?
N-formyl-leucine + H2O
at 0.8-12% of the activity with N-formyl-methionine, depending on tissue
393796
Rattus norvegicus
formate + leucine
-
-
-
?
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
additional information
-
27% more active with phosphate than with Tris-Cl- buffer
Rattus norvegicus
7.4
-
-
Gallus gallus
7.4
-
-
Rattus norvegicus
7.4
-
-
Sus scrofa
7.4
-
-
Bos taurus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.3
-
N-formyl-methionine
enzyme from spleen
Rattus norvegicus
5
-
N-formyl-methionine
enzyme from brain, heart or muscle
Rattus norvegicus
6.5
-
N-formyl-methionine
enzyme from kidney
Rattus norvegicus
12.5
-
N-formyl-methionine
enzyme from liver
Rattus norvegicus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
brain
-
Rattus norvegicus
-
brain
-
Bos taurus
-
heart
-
Rattus norvegicus
-
kidney
-
Rattus norvegicus
-
kidney
-
Sus scrofa
-
liver
-
Gallus gallus
-
liver
-
Rattus norvegicus
-
muscle
-
Rattus norvegicus
-
spleen
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
N-formyl-alanine + H2O
at 2-7% of the activity with N-formyl-methionine, depending on tissue
393796
Rattus norvegicus
formate + alanine
-
-
-
?
N-formyl-L-methionine + H2O
-
393796
Gallus gallus
formate + L-methionine
-
393796
Gallus gallus
?
N-formyl-L-methionine + H2O
-
393796
Rattus norvegicus
formate + L-methionine
-
393796
Rattus norvegicus
?
N-formyl-L-methionine + H2O
-
393796
Sus scrofa
formate + L-methionine
-
393796
Sus scrofa
?
N-formyl-L-methionine + H2O
-
393796
Bos taurus
formate + L-methionine
-
393796
Bos taurus
?
N-formyl-leucine + H2O
at 0.8-12% of the activity with N-formyl-methionine, depending on tissue
393796
Rattus norvegicus
formate + leucine
-
-
-
?
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
additional information
-
27% more active with phosphate than with Tris-Cl- buffer
Rattus norvegicus
7.4
-
-
Gallus gallus
7.4
-
-
Rattus norvegicus
7.4
-
-
Sus scrofa
7.4
-
-
Bos taurus
Other publictions for EC 3.5.1.31
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
393795
Ackerman
N-Formyl-L-methionine deformyl ...
Homo sapiens
Biochem. J.
182
885-887
1979
-
-
-
-
-
-
4
-
1
1
-
1
-
3
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
1
1
-
1
-
-
-
-
-
2
-
-
2
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
393796
Grisolia
N-Formyl-methionine deformylas ...
Bos taurus, Gallus gallus, Rattus norvegicus, Sus scrofa
Biochem. Biophys. Res. Commun.
77
237-244
1977
-
-
-
-
-
-
-
4
-
-
-
-
-
4
-
-
-
-
-
9
-
-
6
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
9
-
-
6
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
393797
Aronson
N-Formylmethionine deformylase ...
Euglena gracilis
Biochem. Biophys. Res. Commun.
34
311-314
1969
-
-
-
-
-
-
-
1
-
-
-
1
-
1
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-