N-Formyl-methionine deformylase of animal tissues

Grisolia, S.; Reglero.A.; Rivas, J.; Biochem. Biophys. Res. Commun. 77, 237-244 (1977)

Data extracted from this reference:

KM Value [mM]

KM Value Maximum [mM]

Substrate

Commentary

Organism

Structure

3.3

-

N-formyl-methionine

enzyme from spleen

Rattus norvegicus

5

-

N-formyl-methionine

enzyme from brain, heart or muscle

Rattus norvegicus

6.5

-

N-formyl-methionine

enzyme from kidney

Rattus norvegicus

12.5

-

N-formyl-methionine

enzyme from liver

Rattus norvegicus

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

Substrate Product ID

N-formyl-alanine + H2O

at 2-7% of the activity with N-formyl-methionine, depending on tissue

393796

Rattus norvegicus

formate + alanine

-

-

-

?

N-formyl-L-methionine + H2O

-

393796

Gallus gallus

formate + L-methionine

-

393796

Gallus gallus

?

N-formyl-L-methionine + H2O

-

393796

Rattus norvegicus

formate + L-methionine

-

393796

Rattus norvegicus

?

N-formyl-L-methionine + H2O

-

393796

Sus scrofa

formate + L-methionine

-

393796

Sus scrofa

?

N-formyl-L-methionine + H2O

-

393796

Bos taurus

formate + L-methionine

-

393796

Bos taurus

?

N-formyl-leucine + H2O

at 0.8-12% of the activity with N-formyl-methionine, depending on tissue

393796

Rattus norvegicus

formate + leucine

-

-

-

?

KM Value [mM]

KM Value Maximum [mM]

Substrate

Commentary

Organism

Structure

3.3

-

N-formyl-methionine

enzyme from spleen

Rattus norvegicus

5

-

N-formyl-methionine

enzyme from brain, heart or muscle

Rattus norvegicus

6.5

-

N-formyl-methionine

enzyme from kidney

Rattus norvegicus

12.5

-

N-formyl-methionine

enzyme from liver

Rattus norvegicus

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

ID

N-formyl-alanine + H2O

at 2-7% of the activity with N-formyl-methionine, depending on tissue

393796

Rattus norvegicus

formate + alanine

-

-

-

?

N-formyl-L-methionine + H2O

-

393796

Gallus gallus

formate + L-methionine

-

393796

Gallus gallus

?

N-formyl-L-methionine + H2O

-

393796

Rattus norvegicus

formate + L-methionine

-

393796

Rattus norvegicus

?

N-formyl-L-methionine + H2O

-

393796

Sus scrofa

formate + L-methionine

-

393796

Sus scrofa

?

N-formyl-L-methionine + H2O

-

393796

Bos taurus

formate + L-methionine

-

393796

Bos taurus

?

N-formyl-leucine + H2O

at 0.8-12% of the activity with N-formyl-methionine, depending on tissue

393796

Rattus norvegicus

formate + leucine

-

-

-

?

No.

1st author

Pub Med

title

organims

journal

volume

pages

year

Activating Compound

Application

Cloned(Commentary)

Crystallization (Commentary)

Engineering

General Stability

Inhibitors

KM Value [mM]

Localization

Metals/Ions

Molecular Weight [Da]

Natural Substrates/ Products (Substrates)

Organic Solvent Stability

Organism

Oxidation Stability

Posttranslational Modification

Purification (Commentary)

Reaction

Renatured (Commentary)

Source Tissue

Specific Activity [micromol/min/mg]

Storage Stability

Substrates and Products (Substrate)

Subunits

Synonyms

Temperature Optimum [°C]

Temperature Range [°C]

Temperature Stability [°C]

Turnover Number [1/s]

pH Optimum

pH Range

pH Stability

Cofactor

Ki Value [mM]

pI Value

IC50 Value

Activating Compound (protein specific)

Application (protein specific)

Cloned(Commentary) (protein specific)

Cofactor (protein specific)

Crystallization (Commentary) (protein specific)

Engineering (protein specific)

General Stability (protein specific)

IC50 Value (protein specific)

Inhibitors (protein specific)

Ki Value [mM] (protein specific)

KM Value [mM] (protein specific)

Localization (protein specific)

Metals/Ions (protein specific)

Molecular Weight [Da] (protein specific)

Natural Substrates/ Products (Substrates) (protein specific)

Organic Solvent Stability (protein specific)

Oxidation Stability (protein specific)

Posttranslational Modification (protein specific)

Purification (Commentary) (protein specific)

Renatured (Commentary) (protein specific)

Source Tissue (protein specific)

Specific Activity [micromol/min/mg] (protein specific)

Storage Stability (protein specific)

Substrates and Products (Substrate) (protein specific)

Subunits (protein specific)

Temperature Optimum [°C] (protein specific)

Temperature Range [°C] (protein specific)

Temperature Stability [°C] (protein specific)

Turnover Number [1/s] (protein specific)

pH Optimum (protein specific)

pH Range (protein specific)

pH Stability (protein specific)

pI Value (protein specific)

Expression

General Information

General Information (protein specific)

Expression (protein specific)

KCat/KM [mM/s]

KCat/KM [mM/s] (protein specific)

393795

Ackerman

N-Formyl-L-methionine deformyl ...

Homo sapiens

Biochem. J.

182

885-887

1979

-

-

-

-

-

-

4

-

1

1

-

1

-

3

-

-

-

-

-

2

-

-

2

-

-

-

-

-

-

2

1

-

-

-

-

-

-

-

-

-

-

-

-

-

4

-

-

1

1

-

1

-

-

-

-

-

2

-

-

2

-

-

-

-

-

2

1

-

-

-

-

-

-

-

-

393796

Grisolia

N-Formyl-methionine deformylas ...

Bos taurus, Gallus gallus, Rattus norvegicus, Sus scrofa

Biochem. Biophys. Res. Commun.

77

237-244

1977

-

-

-

-

-

-

-

4

-

-

-

-

-

4

-

-

-

-

-

9

-

-

6

-

-

-

-

-

-

5

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

4

-

-

-

-

-

-

-

-

-

9

-

-

6

-

-

-

-

-

5

-

-

-

-

-

-

-

-

-

393797

Aronson

N-Formylmethionine deformylase ...

Euglena gracilis

Biochem. Biophys. Res. Commun.

34

311-314

1969

-

-

-

-

-

-

-

1

-

-

-

1

-

1

-

-

-

-

-

-

1

-

3

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

1

-

-

-

-

-

-

1

-

3

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-