Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | 2 mM, 90-100% inhibition | Homo sapiens | |
dithiothreitol | 2 mM, 90-100% inhibition | Homo sapiens | |
EDTA | 2 mM, 65-80% inhibition | Homo sapiens | |
phenylmethanesulfonyl fluoride | 2 mM, 10% inhibition | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | 0.1 mM, 7-10fold stimulation | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme may be important in modulation of neutrophil responses to chemoattractant formylmethionyl peptides or similar compounds | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leukocyte | - |
Homo sapiens | - |
platelet | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme may be important in modulation of neutrophil responses to chemoattractant formylmethionyl peptides or similar compounds | Homo sapiens | ? | - |
? | |
N-formyl-L-methionine + H2O | - |
Homo sapiens | formate + L-methionine | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
activity in 0.1 M Tris buffer is 10fold lower than in 0.1 M phosphate buffer, pH 8.5 | Homo sapiens |
7.5 | - |
- |
Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | 9.5 | pH 6.5: about 75% of maximal activity, pH 9.5: about 50% of maximal activity | Homo sapiens |