Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.5.1.26 extracted from

  • Saarela, J.; Laine, M.; Tikkanen, R.; Oinonen, C.; Jalanko, A.; Rouvinen, J.; Peltonen, L.
    Activation and oligomerization of aspartylglucosaminidase (1998), J. Biol. Chem., 273, 25320-25328.
    View publication on PubMed
Search for more literature for 3.5.1.26

Cloned(Commentary)

Cloned (Comment) Organism
expression in COS cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
D205G essential for activation by autocatalytic proteolytic processing Homo sapiens
H124R reduced dimerization of the precursor polypeptide, total secretion into the medium Homo sapiens
H124W reduced dimerization of the precursor polypeptide, total secretion into the medium Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Homo sapiens 5764
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O Homo sapiens involved in degradation of glycoproteins 2-acetamido-1-amino-1,2-dideoxy-beta-D-glucose + L-aspartate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O involved in degradation of glycoproteins Homo sapiens 2-acetamido-1-amino-1,2-dideoxy-beta-D-glucose + L-aspartate
-
 ?

Subunits

Subunits Comment Organism
tetramer alpha2 + beta2 Homo sapiens