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Literature summary for 3.5.1.25 extracted from

  • Plumbridge, J.
    An alternative route for recycling of N-acetylglucosamine from peptidoglycan involves the N-acetylglucosamine phosphotransferase system in Escherichia coli (2009), J. Bacteriol., 191, 5641-5647.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.1.25

Protein Variants

Protein Variants Comment Organism
additional information mutations in nagA result in accumulation of millimolar of N-acetylglucosamine, presumably by preventing peptidoglycan recycling. Mutations in the genes encoding the key enzymes upstream of nagA in the recycling pathway (amG, nagZ, nagK, murQ, and anmK), which are expected to interrupt the recycling process, reduce but do not eliminate accumulation of N-acetyl-6-phosphate Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acetyl-D-glucosamine 6-phosphate + H2O
-
 Escherichia coli D-glucosamine 6-phosphate + acetate
-
 ?
N-acetyl-D-glucosamine 6-phosphate + H2O
-
 Escherichia coli JW0662 D-glucosamine 6-phosphate + acetate
-
 ?

Synonyms

Synonyms Comment Organism
NagA
-
 Escherichia coli

General Information

General Information Comment Organism
physiological function part of the pathway responsible for the recycling of amino sugar components of peptidoglycan, the cataboloc pathway for the use of N-acetylglucosamine Escherichia coli