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Literature summary for 3.5.1.25 extracted from

  • Wendland, J.; Schaub, Y.; Walther, A.
    N-Acetylglucosamine utilization by Saccharomyces cerevisiae based on expression of Candida albicans NAG genes (2009), Appl. Environ. Microbiol., 75, 5840-5845.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
NAG genes are expressed in Saccharomyces cerevisiae BY strains to study their effect on making novel carbon sources available for Saccharomyces cerevisiae Candida albicans

Organism

Organism UniProt Comment Textmining
Candida albicans
-
 BWP17
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acetyl-D-glucosamine 6-phosphate + H2O
-
 Candida albicans D-glucosamine 6-phosphate + acetate
-
 ?
N-acetyl-D-glucosamine 6-phosphate + H2O
-
 Candida albicans BWP17 D-glucosamine 6-phosphate + acetate
-
 ?

Synonyms

Synonyms Comment Organism
CaNAG2/Dac1
-
 Candida albicans
GlcNAc-6-phosphate deacetylase
-
 Candida albicans
NAG2
-
 Candida albicans

General Information

General Information Comment Organism
physiological function the Candida albicans genes encoding GlcNAc permease, GlcNAc kinase, GlcNAc-6-phosphate deacetylase, and glucosamine-6-phosphate deaminase are expressed in Saccharomyces cerevisiae strains to enable the use of GlcNAc as a carbon source. Chitin is the second abundant polysaccharide after cellulose and consists of N-acetylglucosamine moieties, which cannot be used by wild-type Saccharomyces cerevisiae Candida albicans