Inhibitors | Comment | Organism | Structure |
---|---|---|---|
methyl phosphonamidates inhibitor 1 | tetrahedral reaction intermediate analogues | Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | 1 equivalent of zinc bound at the Mbeta site, the enzyme contains a binuclear metal center at the active site | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-D-glucosamine 6-phosphate + H2O | Escherichia coli | - |
D-glucosamine 6-phosphate + acetate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
gene nagA | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate | catalytic mechanism, enzyme-substrate interaction analysis | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-D-glucosamine 6-phosphate + H2O | - |
Escherichia coli | D-glucosamine 6-phosphate + acetate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NagA | - |
Escherichia coli |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Escherichia coli |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | inhibition kinetics, inhibitor binding model | Escherichia coli | |
0.000034 | - |
methyl phosphonamidates inhibitor 1 | pH 7.5, 30°C, recombinant enzyme | Escherichia coli |