Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.5.1.25 extracted from

  • Campbell, P.; Thompson, J.N.; Fraser, J.R.; Laurent, T.C.; Pertoft, H.; Roden, L.
    N-Acetylglucosamine-6-phosphate deacetylase in hepatocytes, Kupffer cells and sinusoidal endothelial cells from rat liver (1990), Hepatology, 11, 199-204.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N-acetyl-D-glucosamine 6-phosphate + H2O Homo sapiens
-
D-glucosamine 6-phosphate + acetate
-
?
N-acetyl-D-glucosamine 6-phosphate + H2O Rattus norvegicus presence of high deacetylase activity in endothelial cells and Kupffer cells but a virtual lack of activity in hepatocytes, suggests that the major part of the N-acetylglucosamine generated by the catabolism of glycoconjugates in the latter cells is reused in the synthesis of new complex carbohydrate molecules D-glucosamine 6-phosphate + acetate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte extreme low activity Rattus norvegicus
-
Kupffer cell
-
Rattus norvegicus
-
liver sinusoidal endothelial cell
-
Rattus norvegicus
-
skin fibroblast
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acetyl-D-glucosamine 6-phosphate + H2O
-
Homo sapiens D-glucosamine 6-phosphate + acetate
-
?
N-acetyl-D-glucosamine 6-phosphate + H2O
-
Rattus norvegicus D-glucosamine 6-phosphate + acetate
-
?
N-acetyl-D-glucosamine 6-phosphate + H2O presence of high deacetylase activity in endothelial cells and Kupffer cells but a virtual lack of activity in hepatocytes, suggests that the major part of the N-acetylglucosamine generated by the catabolism of glycoconjugates in the latter cells is reused in the synthesis of new complex carbohydrate molecules Rattus norvegicus D-glucosamine 6-phosphate + acetate
-
?