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Literature summary for 3.5.1.24 extracted from

  • Allain, T.; Chaouch, S.; Thomas, M.; Travers, M.A.; Valle, I.; Langella, P.; Grellier, P.; Polack, B.; Florent, I.; Bermudez-Humaran, L.G.
    Bile salt hydrolase activities a novel target to screen anti-giardia Lactobacilli? (2018), Front. Microbiol., 9, 89 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.1.24

Organism

Organism UniProt Comment Textmining
Lactobacillus gasseri
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Lactobacillus gasseri CNCM I-4884
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Synonyms

Synonyms Comment Organism
bile salt hydrolase
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 Lactobacillus gasseri
BSH
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 Lactobacillus gasseri

General Information

General Information Comment Organism
physiological function bile salt hydrolase (BSH)-like activities of Lactobacilli protect against pathogenic infection with Giardia duodenalis. Giardia duodenalis is a protozoan parasite responsible for giardiasis, a disease characterized by intestinal malabsorption, diarrhea and abdominal pain in a large number of mammal species. Giardiasis is one of the most common intestinal parasitic diseases in the world. Several strains are tested, overview. The two most active strains in vitro are Lactobacillus johnsonii strain La1 and Lactobacillus gasseri strain CNCM I-4884. Only Lactobacillus gasseri strain CNCM I-4884 is able to significantly antagonize parasite growth with a dramatic reduction of the Giardia duodenalis strain WB6 trophozoites load in the small intestine Lactobacillus gasseri