Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli BL21(DE3) | Neisseria meningitidis |
Crystallization (Comment) | Organism |
---|---|
sitting-drop vapor-diffusion method at 16°C, three-dimensional X-ray crystal structure of the enzyme in complex with L-captopril at 1.8 A resolution | Neisseria meningitidis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-captopril | competitive inhibitor | Neisseria meningitidis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | EPR and MCD data indicate that the two Co(II) ions in DapE are antiferromagnetically coupled | Neisseria meningitidis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Neisseria meningitidis | Q9JYL2 | - |
- |
Neisseria meningitidis MC58 | Q9JYL2 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-succinyl-LL-2,6-diaminoheptanedioate + H2O | - |
Neisseria meningitidis | succinate + LL-2,6-diaminoheptanedioate | - |
? | |
N-succinyl-LL-2,6-diaminoheptanedioate + H2O | - |
Neisseria meningitidis MC58 | succinate + LL-2,6-diaminoheptanedioate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DapE | - |
Neisseria meningitidis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0028 | - |
L-captopril | 25°C, pH 7.5 | Neisseria meningitidis |