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Literature summary for 3.5.1.14 extracted from

  • Lindner, H.A.; Taefler-Naumann, M.; Roehm, K.H.
    N-acetylamino acid utilization by kidney aminoacylase-1 (2008), Biochimie, 90, 773-780.
    View publication on PubMed
Search for more literature for 3.5.1.14

Cloned(Commentary)

Cloned (Comment) Organism
expression in Baculovirus Sus scrofa
expression in Baculovirus Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
DTT
-
 Homo sapiens
DTT
-
 Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.43
-
 N-acetyl-L-methionine 25°C, pH7.4 Homo sapiens
0.44
-
 N-acetyl-L-norleucine 25°C, pH7.4 Homo sapiens
1.28
-
 N-acetyl-L-ethionine 25°C, pH7.4 Homo sapiens
1.4
-
 N-acetyl-L-cysteine 25°C, pH7.4 Homo sapiens
1.5
-
 N-acetyl-L-cysteine 25°C, pH 7.4 Sus scrofa
1.57
-
 N-acetyl-L-norleucine 25°C, pH 7.4 Sus scrofa
1.87
-
 N-acetyl-L-ethionine 25°C, pH 7.4 Sus scrofa
2.4
-
 N-acetyl-L-leucine 25°C, pH7.4 Homo sapiens
2.72
-
 N-acetyl-L-methionine 25°C, pH 7.4 Sus scrofa
3.8
-
 N-acetyl-L-leucine 25°C, pH 7.4 Sus scrofa
4.81
-
 N-acetyl-L-phenylalanine 25°C, pH7.4 Homo sapiens
6.72
-
 N-acetyl-L-isoleucine 25°C, pH 7.4 Sus scrofa
10.3
-
 N-acetyl-L-phenylalanine 25°C, pH 7.4 Sus scrofa
11.4
-
 N-acetyl-L-valine 25°C, pH7.4 Homo sapiens
11.9
-
 N-acetyl-L-histidine 25°C, pH 7.4 Sus scrofa
16.6
-
 N-acetyl-L-valine 25°C, pH 7.4 Sus scrofa
20.1
-
 N-acetyl-L-alanine 25°C, pH7.4 Homo sapiens
22.7
-
 N-acetyl-L-histidine 25°C, pH7.4 Homo sapiens
27.7
-
 N-acetyl-L-asparagine 25°C, pH7.4 Homo sapiens
30.9
-
 N-acetyl-L-threonine 25°C, pH 7.4 Sus scrofa
32.5
-
 N-acetyl-L-threonine 25°C, pH7.4 Homo sapiens
34.8
-
 N-acetyl-L-arginine 25°C, pH 7.4 Sus scrofa
43.6
-
 N-acetyl-glycine 25°C, pH 7.4 Sus scrofa
57.6
-
 N-acetyl-L-glutamine 25°C, pH 7.4 Sus scrofa
59.9
-
 N-acetyl-glycine 25°C, pH7.4 Homo sapiens
62.3
-
 N-acetyl-L-glutamine 25°C, pH7.4 Homo sapiens
63
-
 N-acetyl-L-glutamate 25°C, pH7.4 Homo sapiens
102
-
 N-acetyl-L-glutamate 25°C, pH 7.4 Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Sus scrofa 5737
-
cytoplasm
-
 Homo sapiens 5737
-

Organism

Organism UniProt Comment Textmining
Homo sapiens Q03154
-
-
Sus scrofa P37111
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Sus scrofa
-
kidney
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acetyl-glycine + H2O
-
 Sus scrofa acetate + glycine
-
 ?
N-acetyl-glycine + H2O
-
 Homo sapiens acetate + glycine
-
 ?
N-acetyl-L-alanine + H2O
-
 Homo sapiens acetate + L-alanine
-
 ?
N-acetyl-L-arginine + H2O
-
 Sus scrofa acetate + L-arginine
-
 ?
N-acetyl-L-asparagine + H2O
-
 Homo sapiens acetate + L-asparagine
-
 ?
N-acetyl-L-cysteine + H2O
-
 Sus scrofa acetate + L-cysteine
-
 ?
N-acetyl-L-cysteine + H2O
-
 Homo sapiens acetate + L-cysteine
-
 ?
N-acetyl-L-ethionine + H2O
-
 Sus scrofa acetate + L-ethionine
-
 ?
N-acetyl-L-ethionine + H2O
-
 Homo sapiens acetate + L-ethionine
-
 ?
N-acetyl-L-glutamate + H2O
-
 Sus scrofa acetate + L-glutamate
-
 ?
N-acetyl-L-glutamate + H2O
-
 Homo sapiens acetate + L-glutamate
-
 ?
N-acetyl-L-glutamine + H2O
-
 Sus scrofa acetate + L-glutamine
-
 ?
N-acetyl-L-glutamine + H2O
-
 Homo sapiens acetate + L-glutamine
-
 ?
N-acetyl-L-histidine + H2O
-
 Sus scrofa acetate + L-histidine
-
 ?
N-acetyl-L-histidine + H2O
-
 Homo sapiens acetate + L-histidine
-
 ?
N-acetyl-L-isoleucine + H2O
-
 Sus scrofa acetate + L-isoleucine
-
 ?
N-acetyl-L-leucine + H2O
-
 Sus scrofa acetate + L-leucine
-
 ?
N-acetyl-L-leucine + H2O
-
 Homo sapiens acetate + L-leucine
-
 ?
N-acetyl-L-methionine + H2O
-
 Sus scrofa acetate + L-methionine
-
 ?
N-acetyl-L-methionine + H2O
-
 Homo sapiens acetate + L-methionine
-
 ?
N-acetyl-L-norleucine + H2O
-
 Sus scrofa acetate + L-norleucine
-
 ?
N-acetyl-L-norleucine + H2O
-
 Homo sapiens acetate + L-norleucine
-
 ?
N-acetyl-L-phenylalanine + H2O
-
 Sus scrofa acetate + L-phenylalanine
-
 ?
N-acetyl-L-phenylalanine + H2O
-
 Homo sapiens acetate + L-phenylalanine
-
 ?
N-acetyl-L-threonine + H2O
-
 Sus scrofa acetate + L-threonine
-
 ?
N-acetyl-L-threonine + H2O
-
 Homo sapiens acetate + L-threonine
-
 ?
N-acetyl-L-valine + H2O
-
 Sus scrofa acetate + L-valine
-
 ?
N-acetyl-L-valine + H2O
-
 Homo sapiens acetate + L-valine
-
 ?
N-acyl-L-amino acid + H2O
-
 Homo sapiens carboxylate + L-amino acid
-
 ?

Synonyms

Synonyms Comment Organism
hAcy1
-
 Homo sapiens
pAcy1
-
 Sus scrofa

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.04 1.97 N-acetyl-L-arginine 25°C, pH 7.4 Sus scrofa
0.14
-
 N-acetyl-L-phenylalanine 25°C, pH7.4 Homo sapiens
0.81
-
 N-acetyl-L-phenylalanine 25°C, pH 7.4 Sus scrofa
1.2
-
 N-acetyl-L-histidine 25°C, pH7.4 Homo sapiens
1.21
-
 N-acetyl-L-threonine 25°C, pH 7.4 Sus scrofa
1.28
-
 N-acetyl-L-isoleucine 25°C, pH 7.4 Sus scrofa
2.23
-
 N-acetyl-L-threonine 25°C, pH7.4 Homo sapiens
2.77
-
 N-acetyl-L-histidine 25°C, pH 7.4 Sus scrofa
7.6
-
 N-acetyl-glycine 25°C, pH 7.4 Sus scrofa
8.53
-
 N-acetyl-L-arginine 25°C, pH 7.4 Sus scrofa
11.9
-
 N-acetyl-L-valine 25°C, pH 7.4 Sus scrofa
12.4
-
 N-acetyl-L-ethionine 25°C, pH7.4 Homo sapiens
14.7
-
 N-acetyl-L-valine 25°C, pH7.4 Homo sapiens
28.1
-
 N-acetyl-L-cysteine 25°C, pH7.4 Homo sapiens
30.7
-
 N-acetyl-L-glutamine 25°C, pH7.4 Homo sapiens
31.7
-
 N-acetyl-glycine 25°C, pH7.4 Homo sapiens
34.7
-
 N-acetyl-L-cysteine 25°C, pH 7.4 Sus scrofa
38.3
-
 N-acetyl-L-methionine 25°C, pH7.4 Homo sapiens
55.5
-
 N-acetyl-L-leucine 25°C, pH7.4 Homo sapiens
68.3
-
 N-acetyl-L-ethionine 25°C, pH 7.4 Sus scrofa
134
-
 N-acetyl-L-methionine 25°C, pH 7.4 Sus scrofa
146
-
 N-acetyl-L-glutamine 25°C, pH 7.4 Sus scrofa
156
-
 N-acetyl-L-glutamate 25°C, pH7.4 Homo sapiens
156
-
 N-acetyl-L-norleucine 25°C, pH7.4 Homo sapiens
160
-
 N-acetyl-L-leucine 25°C, pH 7.4 Sus scrofa
207
-
 N-acetyl-L-glutamate 25°C, pH 7.4 Sus scrofa
266
-
 N-acetyl-L-norleucine 25°C, pH 7.4 Sus scrofa