Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Thermus thermophilus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
[carrier protein LysW]-C-terminal-alpha-(L-lysyl)-L-glutamate | - |
Thermus thermophilus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Thermus thermophilus | for the conversion of alpha-aminoadipate to lysine, the amino group of alpha-aminoadipate is modified by attachment to the gamma-carboxyl group of the C-terminal Glu54 of a small protein, LysW. The side chain of alpha-aminoadipate is converted to the lysyl side chain while still attached to LysW, and lysine is subsequently liberated from the LysW-lysine fusion | ? | - |
? | |
additional information | Thermus thermophilus DSM 7039 | for the conversion of alpha-aminoadipate to lysine, the amino group of alpha-aminoadipate is modified by attachment to the gamma-carboxyl group of the C-terminal Glu54 of a small protein, LysW. The side chain of alpha-aminoadipate is converted to the lysyl side chain while still attached to LysW, and lysine is subsequently liberated from the LysW-lysine fusion | ? | - |
? | |
[carrier protein LysW]-C-terminal-gamma-(L-lysyl)-L-glutamate + H2O | Thermus thermophilus | - |
[carrier protein LysW]-C-terminal-L-glutamate + L-lysine | - |
? | |
[carrier protein LysW]-C-terminal-gamma-(L-lysyl)-L-glutamate + H2O | Thermus thermophilus DSM 7039 | - |
[carrier protein LysW]-C-terminal-L-glutamate + L-lysine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermus thermophilus | Q8VUS5 | - |
- |
Thermus thermophilus DSM 7039 | Q8VUS5 | - |
- |
Purification (Comment) | Organism |
---|---|
recombinant protein | Thermus thermophilus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | for the conversion of alpha-aminoadipate to lysine, the amino group of alpha-aminoadipate is modified by attachment to the gamma-carboxyl group of the C-terminal Glu54 of a small protein, LysW. The side chain of alpha-aminoadipate is converted to the lysyl side chain while still attached to LysW, and lysine is subsequently liberated from the LysW-lysine fusion | Thermus thermophilus | ? | - |
? | |
additional information | no substrates: [carrier protein LysW]-C-terminal-alpha-(L-lysyl)-L-glutamate, [carrier protein LysW]-13-alpha-(L-lysyl)-L-glutamate | Thermus thermophilus | ? | - |
? | |
additional information | for the conversion of alpha-aminoadipate to lysine, the amino group of alpha-aminoadipate is modified by attachment to the gamma-carboxyl group of the C-terminal Glu54 of a small protein, LysW. The side chain of alpha-aminoadipate is converted to the lysyl side chain while still attached to LysW, and lysine is subsequently liberated from the LysW-lysine fusion | Thermus thermophilus DSM 7039 | ? | - |
? | |
additional information | no substrates: [carrier protein LysW]-C-terminal-alpha-(L-lysyl)-L-glutamate, [carrier protein LysW]-13-alpha-(L-lysyl)-L-glutamate | Thermus thermophilus DSM 7039 | ? | - |
? | |
[carrier protein LysW]-C-terminal-gamma-(L-lysyl)-L-glutamate + H2O | - |
Thermus thermophilus | [carrier protein LysW]-C-terminal-L-glutamate + L-lysine | - |
? | |
[carrier protein LysW]-C-terminal-gamma-(L-lysyl)-L-glutamate + H2O | - |
Thermus thermophilus DSM 7039 | [carrier protein LysW]-C-terminal-L-glutamate + L-lysine | - |
? |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00067 | - |
pH 8.0, 60°C | Thermus thermophilus | [carrier protein LysW]-C-terminal-alpha-(L-lysyl)-L-glutamate |