Literature summary for 3.5.1.13 extracted from

Chinnadurai, R.K.; Saravanaraman, P.; Boopathy, R.
The significance of aryl acylamidase activity of acetylcholinesterase in osteoblast differentiation and mineralization (2018), Mol. Cell. Biochem., 440, 199-208 .

Search for more literature for 3.5.1.13

Inhibitors

Inhibitors	Comment	Organism	Structure
edrophonium	activity is reduced to 64.1% and 30.7% at 0.1 and 0.5 mM. Edrophonium inhibits esterase activity and aryl acylamidase activity of acetylcholinesterase	Homo sapiens
additional information	gallamine selectively inhibits the esterase activity to 63.6% (0.1 mM) and 45.4% (0.5 mM), whereas the aryl acylamidase activity remains significantly unaltered in the presence of gallamine (0.1 mM: 105.2%. 0.5 mM: 107%)	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P22303	cf. EC 3.1.1.7	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
SAOS-2 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-nitroacetanilide + H2O	-	Homo sapiens	2-nitroaniline + acetate	-	?

General Information

General Information	Comment	Organism
physiological function	aryl acylamidase activity of acetylcholinesterase is actively involved in the process of osteoblast differentiation and mineralization	Homo sapiens

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Release 2023.1 (January 2023)