BRENDA - Enzyme Database
show all sequences of 3.5.1.13

Nitrilase superfamily aryl acylamidase from the halotolerant mangrove Streptomyces sp. 211726

Ma, Y.; Xu, W.; Zhang, J.; Zhang, S.; Hong, K.; Deng, Z.; Sun, Y.; Appl. Microbiol. Biotechnol. 98, 8583-8590 (2014)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
additional information
no effect by EDTA, 8-hydroxyquinoline, and 2-mercaptoethanol
Streptomyces sp.
PMSF
slight activation at 1 mM
Streptomyces sp.
Cloned(Commentary)
Cloned (Commentary)
Organism
gene azl13, DNA and amino acid sequence determination and analysis, sequence comparison, recombinant expression of His6-tagged wild-type and mutant enzymes in Escherichia coli strain BL21(DE3)
Streptomyces sp.
Engineering
Protein Variants
Commentary
Organism
C141A
site-directed mutagenesis, inactive mutant
Streptomyces sp.
E41A
site-directed mutagenesis, inactive mutant
Streptomyces sp.
K107A
site-directed mutagenesis, inactive mutant
Streptomyces sp.
Inhibitors
Inhibitors
Commentary
Organism
Structure
Ag+
complete inhibition at 1 mM
Streptomyces sp.
Cd2+
complete inhibition at 1 mM
Streptomyces sp.
Cu2+
complete inhibition at 1 mM
Streptomyces sp.
Hg2+
complete inhibition at 1 mM
Streptomyces sp.
additional information
no effect by EDTA, 8-hydroxyquinoline, and 2-mercaptoethanol
Streptomyces sp.
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
additional information
no requirement for metal ions
Streptomyces sp.
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
31000
-
x * 31000, recombinant His-tagged enzyme, SDS-PAGE
Streptomyces sp.
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
additional information
Streptomyces sp.
4-guanidinobutyramide probably is the natural substrate
?
-
-
-
additional information
Streptomyces sp. 211726
4-guanidinobutyramide probably is the natural substrate
?
-
-
-
Organism
Organism
UniProt
Commentary
Textmining
Streptomyces sp.
A0A088BHP3
gene azl13
-
Streptomyces sp. 211726
A0A088BHP3
gene azl13
-
Purification (Commentary)
Purification (Commentary)
Organism
recombinant His6-tagged wild-type and mutant enzymes from Escherichia coli strain BL21(DE3) by nickel affinity chromatography
Streptomyces sp.
Source Tissue
Source Tissue
Commentary
Organism
Textmining
additional information
halotolerant organism from mangrove swamps
Streptomyces sp.
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.55
-
recombinant purified His-tagged enzyme, pH 8.0, 35°C, substrate 3',4'-dichloropropionanilide
Streptomyces sp.
0.69
-
recombinant purified His-tagged enzyme, pH 8.0, 35°C, substrate 2',6'-dimethylacetanilide
Streptomyces sp.
0.87
-
recombinant purified His-tagged enzyme, pH 8.0, 35°C, substrate p-acetotoluidide
Streptomyces sp.
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
2',6'-dimethylacetanilide + H2O
-
733190
Streptomyces sp.
?
-
-
-
?
2',6'-dimethylacetanilide + H2O
-
733190
Streptomyces sp. 211726
?
-
-
-
?
3',4'-dichloropropionanilide + H2O
i.e. propanil
733190
Streptomyces sp.
3,4-dichloroaniline + propionate
-
-
-
?
3',4'-dichloropropionanilide + H2O
i.e. propanil
733190
Streptomyces sp. 211726
3,4-dichloroaniline + propionate
-
-
-
?
additional information
4-guanidinobutyramide probably is the natural substrate
733190
Streptomyces sp.
?
-
-
-
-
additional information
substrate specificity, overview. The recombinant enzyme displays an unusually wide substrate spectrum. It is moderately active on short-chain aliphatic amides and weakly active hydrolyzing aromatic and heterocyclic amides. Recombinant His6-tagged enzyme Azl13 also catalyzes acyl transfer to hydroxylamine from acetamide or the herbicide propanil. The enzyme also shows amidase, EC 3.5.1.4, and hydroxylamine acyl transferase activity, EC 2.3.1.56. No activity with benzonitrile. phenylacetonitrile, Flutolanil, L-glutamine, and L-asparagine
733190
Streptomyces sp.
?
-
-
-
-
additional information
4-guanidinobutyramide probably is the natural substrate
733190
Streptomyces sp. 211726
?
-
-
-
-
additional information
substrate specificity, overview. The recombinant enzyme displays an unusually wide substrate spectrum. It is moderately active on short-chain aliphatic amides and weakly active hydrolyzing aromatic and heterocyclic amides. Recombinant His6-tagged enzyme Azl13 also catalyzes acyl transfer to hydroxylamine from acetamide or the herbicide propanil. The enzyme also shows amidase, EC 3.5.1.4, and hydroxylamine acyl transferase activity, EC 2.3.1.56. No activity with benzonitrile. phenylacetonitrile, Flutolanil, L-glutamine, and L-asparagine
733190
Streptomyces sp. 211726
?
-
-
-
-
p-acetotoluidide + H2O
-
733190
Streptomyces sp.
?
-
-
-
?
p-acetotoluidide + H2O
-
733190
Streptomyces sp. 211726
?
-
-
-
?
Subunits
Subunits
Commentary
Organism
?
x * 31000, recombinant His-tagged enzyme, SDS-PAGE
Streptomyces sp.
Synonyms
Synonyms
Commentary
Organism
aryl acylamidase
-
Streptomyces sp.
Azl13
-
Streptomyces sp.
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
40
-
-
Streptomyces sp.
Temperature Range [°C]
Temperature Minimum [°C]
Temperature Maximum [°C]
Commentary
Organism
15
60
activity range
Streptomyces sp.
Temperature Stability [°C]
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
40
-
purified His6-tagged enzyme, pH 8.0, stable at for 1 h
Streptomyces sp.
45
50
purified His6-tagged enzyme, pH 8.0, 1 h, 50% activity remaining
Streptomyces sp.
60
-
purified His6-tagged enzyme, pH 8.0, 1 h, inactivation
Streptomyces sp.
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Streptomyces sp.
pH Range
pH Minimum
pH Maximum
Commentary
Organism
5.5
10
activity range
Streptomyces sp.
pH Stability
pH Stability
pH Stability Maximum
Commentary
Organism
4.5
10
purified His6-tagged enzyme, over 50% activity remaining within this range after 1 h
Streptomyces sp.
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
additional information
no effect by EDTA, 8-hydroxyquinoline, and 2-mercaptoethanol
Streptomyces sp.
PMSF
slight activation at 1 mM
Streptomyces sp.
Cloned(Commentary) (protein specific)
Commentary
Organism
gene azl13, DNA and amino acid sequence determination and analysis, sequence comparison, recombinant expression of His6-tagged wild-type and mutant enzymes in Escherichia coli strain BL21(DE3)
Streptomyces sp.
Engineering (protein specific)
Protein Variants
Commentary
Organism
C141A
site-directed mutagenesis, inactive mutant
Streptomyces sp.
E41A
site-directed mutagenesis, inactive mutant
Streptomyces sp.
K107A
site-directed mutagenesis, inactive mutant
Streptomyces sp.
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
Ag+
complete inhibition at 1 mM
Streptomyces sp.
Cd2+
complete inhibition at 1 mM
Streptomyces sp.
Cu2+
complete inhibition at 1 mM
Streptomyces sp.
Hg2+
complete inhibition at 1 mM
Streptomyces sp.
additional information
no effect by EDTA, 8-hydroxyquinoline, and 2-mercaptoethanol
Streptomyces sp.
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
additional information
no requirement for metal ions
Streptomyces sp.
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
31000
-
x * 31000, recombinant His-tagged enzyme, SDS-PAGE
Streptomyces sp.
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
additional information
Streptomyces sp.
4-guanidinobutyramide probably is the natural substrate
?
-
-
-
additional information
Streptomyces sp. 211726
4-guanidinobutyramide probably is the natural substrate
?
-
-
-
Purification (Commentary) (protein specific)
Commentary
Organism
recombinant His6-tagged wild-type and mutant enzymes from Escherichia coli strain BL21(DE3) by nickel affinity chromatography
Streptomyces sp.
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
additional information
halotolerant organism from mangrove swamps
Streptomyces sp.
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.55
-
recombinant purified His-tagged enzyme, pH 8.0, 35°C, substrate 3',4'-dichloropropionanilide
Streptomyces sp.
0.69
-
recombinant purified His-tagged enzyme, pH 8.0, 35°C, substrate 2',6'-dimethylacetanilide
Streptomyces sp.
0.87
-
recombinant purified His-tagged enzyme, pH 8.0, 35°C, substrate p-acetotoluidide
Streptomyces sp.
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
2',6'-dimethylacetanilide + H2O
-
733190
Streptomyces sp.
?
-
-
-
?
2',6'-dimethylacetanilide + H2O
-
733190
Streptomyces sp. 211726
?
-
-
-
?
3',4'-dichloropropionanilide + H2O
i.e. propanil
733190
Streptomyces sp.
3,4-dichloroaniline + propionate
-
-
-
?
3',4'-dichloropropionanilide + H2O
i.e. propanil
733190
Streptomyces sp. 211726
3,4-dichloroaniline + propionate
-
-
-
?
additional information
4-guanidinobutyramide probably is the natural substrate
733190
Streptomyces sp.
?
-
-
-
-
additional information
substrate specificity, overview. The recombinant enzyme displays an unusually wide substrate spectrum. It is moderately active on short-chain aliphatic amides and weakly active hydrolyzing aromatic and heterocyclic amides. Recombinant His6-tagged enzyme Azl13 also catalyzes acyl transfer to hydroxylamine from acetamide or the herbicide propanil. The enzyme also shows amidase, EC 3.5.1.4, and hydroxylamine acyl transferase activity, EC 2.3.1.56. No activity with benzonitrile. phenylacetonitrile, Flutolanil, L-glutamine, and L-asparagine
733190
Streptomyces sp.
?
-
-
-
-
additional information
4-guanidinobutyramide probably is the natural substrate
733190
Streptomyces sp. 211726
?
-
-
-
-
additional information
substrate specificity, overview. The recombinant enzyme displays an unusually wide substrate spectrum. It is moderately active on short-chain aliphatic amides and weakly active hydrolyzing aromatic and heterocyclic amides. Recombinant His6-tagged enzyme Azl13 also catalyzes acyl transfer to hydroxylamine from acetamide or the herbicide propanil. The enzyme also shows amidase, EC 3.5.1.4, and hydroxylamine acyl transferase activity, EC 2.3.1.56. No activity with benzonitrile. phenylacetonitrile, Flutolanil, L-glutamine, and L-asparagine
733190
Streptomyces sp. 211726
?
-
-
-
-
p-acetotoluidide + H2O
-
733190
Streptomyces sp.
?
-
-
-
?
p-acetotoluidide + H2O
-
733190
Streptomyces sp. 211726
?
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 31000, recombinant His-tagged enzyme, SDS-PAGE
Streptomyces sp.
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
40
-
-
Streptomyces sp.
Temperature Range [°C] (protein specific)
Temperature Minimum [°C]
Temperature Maximum [°C]
Commentary
Organism
15
60
activity range
Streptomyces sp.
Temperature Stability [°C] (protein specific)
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
40
-
purified His6-tagged enzyme, pH 8.0, stable at for 1 h
Streptomyces sp.
45
50
purified His6-tagged enzyme, pH 8.0, 1 h, 50% activity remaining
Streptomyces sp.
60
-
purified His6-tagged enzyme, pH 8.0, 1 h, inactivation
Streptomyces sp.
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Streptomyces sp.
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
5.5
10
activity range
Streptomyces sp.
pH Stability (protein specific)
pH Stability
pH Stability Maximum
Commentary
Organism
4.5
10
purified His6-tagged enzyme, over 50% activity remaining within this range after 1 h
Streptomyces sp.
General Information
General Information
Commentary
Organism
evolution
the enzyme belongs to the nitrilase superfamily, subfamily in branch 13. The enzyme contains highly conserved E41-K107-C141 catalytic triad which is typical for nitrilase superfamily amidases
Streptomyces sp.
General Information (protein specific)
General Information
Commentary
Organism
evolution
the enzyme belongs to the nitrilase superfamily, subfamily in branch 13. The enzyme contains highly conserved E41-K107-C141 catalytic triad which is typical for nitrilase superfamily amidases
Streptomyces sp.
Other publictions for EC 3.5.1.13
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
754722
Chinnadurai
The significance of aryl acyl ...
Homo sapiens
Mol. Cell. Biochem.
440
199-208
2018
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
752591
Chinnadurai
Understanding the molecular m ...
Homo sapiens
Arch. Biochem. Biophys.
580
1-13
2015
-
-
-
-
-
-
3
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
752657
Lee
Crystal structure analysis of ...
bacterium CSBL00001
Biochem. Biophys. Res. Commun.
467
268-274
2015
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
733190
Ma
Nitrilase superfamily aryl acy ...
Streptomyces sp. 211726, Streptomyces sp.
Appl. Microbiol. Biotechnol.
98
8583-8590
2014
2
-
1
-
3
-
5
-
-
1
1
2
-
5
-
-
1
-
-
1
3
-
10
1
2
1
1
3
-
1
1
1
-
-
-
-
2
-
1
-
-
3
-
-
5
-
-
-
1
1
2
-
-
-
1
-
1
3
-
10
1
1
1
3
-
1
1
1
-
-
1
1
-
-
-
718672
Shen
Cloning and characterization o ...
Paracoccus sp. M1-1
Appl. Microbiol. Biotechnol.
94
1007-1018
2012
-
-
1
-
3
-
17
3
-
3
2
-
-
3
-
-
1
-
-
-
1
1
7
1
4
1
1
4
3
1
3
4
-
-
1
-
-
-
1
-
-
3
-
-
17
-
3
-
3
2
-
-
-
-
1
-
-
1
1
7
1
1
1
4
3
1
3
4
1
-
2
2
-
3
3
720273
Acero
-
Two-step enzymatic functionali ...
Nocardia farcinica, Nocardia farcinica IFM 10152
J. Mol. Catal. B
79
54-60
2012
-
-
-
-
-
-
-
1
-
-
1
-
-
3
-
-
1
-
-
-
1
-
2
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
1
-
-
1
-
2
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
713035
Ko
Molecular characterization of ...
bacterium CSBL00001
Mol. Cells
29
485-492
2010
-
-
1
-
-
-
5
4
-
-
-
5
-
2
-
-
-
-
-
-
-
-
7
-
2
1
-
4
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
5
-
4
-
-
-
5
-
-
-
-
-
-
-
-
7
-
1
-
4
-
2
-
-
-
-
-
-
-
-
-
696876
Heumann
A novel aryl acylamidase from ...
Nocardia farcinica
Biotechnol. Bioeng.
102
1003-1011
2009
-
-
-
-
-
-
4
2
-
-
3
-
-
4
-
-
1
-
-
-
1
2
13
1
2
1
-
1
2
1
1
-
-
4
-
-
-
-
-
-
-
-
-
-
4
4
2
-
-
3
-
-
-
-
1
-
-
1
2
13
1
1
-
1
2
1
1
-
-
-
-
-
-
-
-
697902
Montenegro
Hydrolysis of acetylthiocoline ...
Bos taurus
FEBS J.
276
2074-2083
2009
-
-
-
-
-
-
2
2
-
-
-
-
-
3
-
-
1
-
-
1
1
-
2
1
1
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
-
1
-
1
1
-
2
1
-
-
-
2
-
-
-
-
-
-
-
-
-
-
711318
Rajesh
The aryl acylamidase activity ...
Gallus gallus
Biochimie
91
1087-1094
2009
-
-
-
-
-
-
4
-
-
-
-
-
-
3
-
-
1
-
-
3
-
-
1
-
1
1
-
-
-
1
-
-
-
-
-
3
-
-
-
-
-
-
-
3
4
-
-
-
-
-
-
-
-
-
1
-
3
-
-
1
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
711319
Rajesh
High aryl acylamidase activity ...
Bungarus, Daboia russelii, Echis carinatus, Naja oxiana
Biochimie
91
1450-1456
2009
-
4
-
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678541
Montenegro
Human butyrylcholinesterase co ...
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Montenegro
The level of aryl acylamidase ...
Homo sapiens
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2008
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3
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1
1
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697309
Li
Binding and hydrolysis of soma ...
Homo sapiens
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2008
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1
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697867
Masson
Kinetic analysis of effector m ...
Homo sapiens
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2
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10
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10
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678058
Peterson
The dependence of enzyme activ ...
Pseudomonas fluorescens
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1
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1
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1
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679287
Boopathy
Human serum cholinesterase fro ...
Homo sapiens
Clin. Chim. Acta
380
151-156
2007
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1
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2
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5
21
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1
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681110
Masson
Aryl acylamidase activity of h ...
Homo sapiens
J. Enzyme Inhib. Med. Chem.
22
463-469
2007
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667330
Manoharan
Diisopropylfluorophosphate-sen ...
Homo sapiens
Arch. Biochem. Biophys.
452
186-188
2006
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1
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6
1
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6
1
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2
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1
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1
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667928
Darvesh
On the active site for hydroly ...
Homo sapiens, Pseudomonas fluorescens
Bioorg. Med. Chem.
14
4586-4599
2006
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8
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1
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1
2
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27
1
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2
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11
2
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8
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1
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1
2
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27
1
2
-
-
11
2
-
-
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-
-
-
-
-
-
668239
Allebrandt
Expression of acetylcholineste ...
Danio rerio
Chem. Biol. Interact.
157-158
353-355
2005
-
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2
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1
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3
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1
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2
-
1
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-
-
1
-
-
-
-
-
-
-
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-
670800
Boopathy
Aryl acylamidase activity on a ...
Gallus gallus
Protein J.
23
325-333
2004
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-
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2
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-
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2
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1
1
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3
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2
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1
1
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1
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2
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1
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3
-
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2
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1
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-
1
-
-
-
-
-
-
-
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-
657938
Stein
Enzymatic hydrolysis of p-nitr ...
Pseudomonas fluorescens
Biochemistry
41
991-1000
2002
-
-
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3
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2
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2
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1
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1
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3
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-
-
2
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-
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1
-
-
-
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-
-
-
-
208992
Weitnauer
Aryl acylamidase activity exhi ...
Equus caballus, Gallus gallus
Neurosci. Lett.
254
153-156
1998
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-
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2
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6
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4
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2
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2
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4
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
208994
Costagli
Inhibition of cholinesterase-a ...
Electrophorus electricus, Equus caballus
Biochem. Pharmacol.
55
1733-1737
1998
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-
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28
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4
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3
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3
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-
28
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3
-
-
3
-
-
-
-
-
-
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-
-
-
-
-
-
-
-
208993
Fukuda
Crystallization and preliminar ...
Tulipa gesneriana
Acta Crystallogr. Sect. D
53
342-344
1997
-
-
-
1
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-
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1
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2
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1
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1
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1
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1
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1
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1
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1
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1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
208991
Hoagland
-
Rhizobacteria with exceptional ...
Pseudomonas sp., Pseudomonas sp. RA2
Pestic. Biochem. Physiol.
52
190-200
1995
-
-
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1
6
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2
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8
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1
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6
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2
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-
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8
-
-
-
-
-
-
-
-
-
-
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-
-
-
-
208971
Villarreal
A structure-activity study wit ...
Acinetobacter sp., Acinetobacter sp. DV1, Arthrobacter sp., Corynebacterium sp., Corynebacterium sp. DAK12
Appl. Environ. Microbiol.
60
3939-3944
1994
-
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10
-
5
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10
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10
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-
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
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208996
Checler
Cholinesterases display genuin ...
Electrophorus electricus
J. Neurochem.
62
756-763
1994
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1
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1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
208997
Jayanthi
Cholinesterases exhibiting ary ...
Homo sapiens
Clin. Chim. Acta
205
157-166
1992
1
-
-
-
-
-
1
-
-
-
-
-
-
2
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1
-
-
2
-
-
1
-
-
-
-
-
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-
-
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-
-
1
-
-
-
-
-
-
-
1
-
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-
-
-
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1
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
208989
Khanna
Characteristics of a cytosolic ...
Felis catus, Homo sapiens, Mus musculus, Rattus norvegicus
J. Pharmacol. Exp. Ther.
262
1225-1231
1991
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7
1
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4
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3
-
-
1
-
-
-
-
-
-
1
1
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-
-
-
-
-
-
-
-
-
-
-
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7
-
1
1
2
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-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
208990
Jun
-
The propanil hydrolyzing enzym ...
Oryza alta, Oryza australiensis, Oryza barthii, Oryza coarctata, Oryza collina, Oryza eichingeri, Oryza glaberrima, Oryza grandiglumis, Oryza latifolia, Oryza longiglumis, Oryza longistaminata, Oryza malabarensis, Oryza meyeriana var. granulata, Oryza minuta, Oryza officinalis, Oryza punctata, Oryza ridleyi, Oryza rufipogon, Oryza sativa
Pestic. Biochem. Physiol.
38
26-33
1990
-
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12
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-
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19
-
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-
-
-
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19
-
-
12
-
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
19
-
12
-
-
-
12
-
-
-
-
-
-
-
-
-
208995
Vaughan
Aryl acylamidase from Rhodococ ...
Rhodococcus erythropolis
Appl. Microbiol. Biotechnol.
34
42-46
1990
-
-
-
-
-
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-
1
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1
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3
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-
1
-
-
-
-
-
3
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-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
1
-
-
-
-
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
208969
Boopathy
Chemical modification of the b ...
Homo sapiens
Eur. J. Biochem.
151
351-360
1985
-
-
-
-
-
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7
-
-
-
-
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2
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-
-
2
-
-
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-
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-
-
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-
-
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-
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7
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-
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-
-
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-
-
2
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
208970
Majumdar
Chemical modification of acety ...
Electrophorus electricus, Ovis aries
Biochemistry
23
4088-4093
1984
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5
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3
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2
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2
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-
-
-
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-
-
-
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-
-
-
-
-
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5
-
-
-
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-
-
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
208972
Gaynor
Subcellular localization of ri ...
Oryza sativa
Plant Physiol.
72
80-85
1983
-
-
-
-
-
-
-
-
2
-
-
1
-
3
-
-
-
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
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-
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-
-
-
2
-
-
1
-
-
-
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
208973
Hammond
Purification and properties of ...
Pseudomonas fluorescens
Eur. J. Biochem.
132
651-655
1983
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-
-
-
-
-
3
2
-
-
2
-
-
2
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-
1
-
-
-
1
2
2
1
-
1
1
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
2
-
-
2
-
-
-
-
1
-
-
1
2
2
1
1
1
1
-
1
1
-
-
-
-
-
-
-
-
208974
Hsu
Brain aryl acylamidase ...
Rattus norvegicus
Int. J. Biochem.
14
1037-1042
1982
-
-
-
-
-
-
1
-
4
-
-
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
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-
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-
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1
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4
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-
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1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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208975
Hsu
Rat brain aryl acylamidase: fu ...
Rattus norvegicus
Int. J. Biochem.
14
581-584
1982
7
-
-
-
-
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9
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2
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2
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7
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9
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2
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-
-
-
-
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208976
Majumdar
Essential and non-essential ph ...
Ovis aries
FEBS Lett.
146
335-338
1982
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1
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1
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208977
George
The aryl acylamidases and thei ...
Homo sapiens
Eur. J. Biochem.
121
177-186
1981
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208978
George
The identity of the serotonin- ...
Electrophorus electricus, Homo sapiens, Ovis aries
Eur. J. Biochem.
111
511-524
1980
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8
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208979
Oommen
The association of the seroton ...
Platyrrhini
Eur. J. Biochem.
94
135-143
1979
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15
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208980
Nakadai
-
Properties of arylamidase from ...
Aspergillus oryzae
Agric. Biol. Chem.
42
1291-1292
1978
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11
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11
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13
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4
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1
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208981
Heymann
The active site of an inducibl ...
Delftia acidovorans
Int. J. Pept. Protein Res.
11
59-64
1978
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208982
Hsu
Rat brain aryl acylamidase: mu ...
Rattus norvegicus
Life Sci.
20
857-866
1977
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4
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208983
Fujimoto
Serotonin-sensitive aryl acyla ...
Electrophorus electricus, Sus scrofa
FEBS Lett.
71
121-123
1976
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2
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208984
Paul
Rat brain de-acetylating activ ...
Rattus norvegicus
Biochem. Biophys. Res. Commun.
70
207-211
1976
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7
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7
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208985
Hoagland
-
Hydrolysis of 3',4'-dichloropr ...
Taraxacum officinale
Phytochemistry
14
383-386
1975
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9
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1
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208986
Hoagland
The purification and propertie ...
Glycine max
Can. J. Biochem.
52
903-910
1974
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208987
Fujimoto
Serotonin-sensitive aryl acyla ...
Rattus norvegicus
Biochem. Biophys. Res. Commun.
61
72-74
1974
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2
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208988
Engelhardt
Purification and properties of ...
Lysinibacillus sphaericus
Appl. Microbiol.
26
709-718
1973
-
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1
10
4
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10
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1
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