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Literature summary for 3.5.1.13 extracted from
- The association of the serotonin-sensitive aryl acylamidase with acetylcholinesterase in the monkey brain (1979), Eur. J. Biochem., 94, 135-143.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| acetyl-beta-methylcholine bromide | - |
Platyrrhini |  |
| Acetylcholine | serotonin-sensitive aryl acylamidase is inhibited, serotonin-insensitive aryl acylamidase is not inhibited | Platyrrhini | |
| acetylcholine iodide | - |
Platyrrhini | |
| acetylthiocholine iodide | - |
Platyrrhini | |
| benzoylcholine chloride | - |
Platyrrhini | |
| Butyrylcholine iodide | - |
Platyrrhini | |
| choline chloride | - |
Platyrrhini | |
| eserine | 0.01 mM, complete, non-competitive | Platyrrhini | |
| neostigmine | 0.01 mM, complete, non-competitive | Platyrrhini | |
| propionylcholine chloride | - |
Platyrrhini | |
| serotonin | serotonin-sensitive aryl acylamidase, serotonin-insensitive aryl acylamidase is not inhibited | Platyrrhini | |
| serotonin creatinine sulfate | - |
Platyrrhini | |
| Succinylcholine chloride | - |
Platyrrhini | |
| tetraisopropyldiphosphoramide | weak | Platyrrhini | |
| tryptamine hydrochloride | - |
Platyrrhini | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | serotonin-sensitive enzyme | Platyrrhini | - |
- |
| synaptosome | serotonin-sensitive enzyme | Platyrrhini | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Platyrrhini | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| serotonin-sensitive enzyme | Platyrrhini |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Platyrrhini | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.016 | - |
- |
Platyrrhini |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | serotonin-sensitive aryl acylamidase is associated with acetylcholinesterase, serotonin-insensitive aryl acylamidase is not associated with acetylcholinesterase | Platyrrhini | ? | - |
? | |
| o-nitroacetanilide + H2O | - |
Platyrrhini | 2-nitroaniline + acetate | - |
? | |
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