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Literature summary for 3.5.1.11 extracted from
- Penicillin acylase and O-aryloxycarbonyl hydroxamates Two acyl-enzymes, one leading to hydrolysis, the other to inactivation (2017), Arch. Biochem. Biophys., 614, 65-71 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| benzothiophene-2-boronic acid | fast reversible competitive inhibitor | Escherichia coli |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.081 | - |
2-nitro-5-phenylacetamidobenzoic acid | pH 7.5, 25°C | Escherichia coli | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-nitro-5-phenylacetamidobenzoic acid + H2O | - |
Escherichia coli | phenylacetate + 2-aminobenzoic acid | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| penicillin acylase | - |
Escherichia coli |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0086 | - |
benzothiophene-2-boronic acid | pH 7.5, 25°C | Escherichia coli | |
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