Application | Comment | Organism |
---|---|---|
synthesis | immobilized penicillin G acylase derivatives are biocatalysts that are industrially used for the hydrolysis of Penicillin G by fermentation and for the kinetically controlled synthesis of semi-synthetic beta-lactam antibiotics. The desired orientation of immobilized enzyme with the active site freely accessible can be obtained by increasing the density of Lys residues on a predetermined region of the enzyme. The designed biocatalysts display improved synthetic performances and are able to maintain a similar activity to the free enzymes. The activity of the immobilized enzyme proportionally improves with the number of introduced Lys | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
penicillin G acylase | - |
Escherichia coli |