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Literature summary for 3.4.99.B1 extracted from

  • Hollander, I.J.; Frommer, E.; Aulabaugh, A.; Mallon, R.
    Human Ras converting enzyme endoproteolytic specificity at the P2' and P3' positions of K-Ras-derived peptides (2003), Biochim. Biophys. Acta, 1649, 24-29.
    View publication on PubMed
Search for more literature for 3.4.99.B1

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme is responsible for one step in Ras membrane localization ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
KSKTKC(farnesyl)VI + H2O a better substrate for hRCE1 than a KSKTKC(f)VIM Homo sapiens ?
-
 ?
additional information the enzyme is responsible for one step in Ras membrane localization Homo sapiens ?
-
 ?
additional information when hRCE1 activity is examined on the same K-Ras core peptide with H-Ras (VLS) or N-Ras (VVM) C-terminal AAX sequences, in each case, the CAA peptides are better hRCE1 substrates. For each peptide set the P2' (A) and P3' (X) positions appear independent in influencing hRCE1 activity on peptide substrates. The P3' position methionine is better than serine; while at the P2' position, isoleucine and valine are better than leucine Homo sapiens ?
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 ?

Synonyms

Synonyms Comment Organism
Ras converting enzyme
-
 Homo sapiens