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Literature summary for 3.4.99.B1 extracted from

  • Michaelson, D.; Ali, W.; Chiu, V.K.; Bergo, M.; Silletti, J.; Wright, L.; Young, S.G.; Philips, M.
    Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases (2005), Mol. Biol. Cell, 16, 1606-1616.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information MEF cells lacking Rce1 Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
littermate embryo
-

Source Tissue

Source Tissue Comment Organism Textmining
MEF cell
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information In MEF cells lacking Rce1, farnesylated Ras proteins are mislocalized, intracellular localizations of geranylated Rho GTPases are not perturbed, RhoGDI binding and actin remodeling is normal in Rce1-deficient cells, swapping geranylgernalytion for farnesylation on Ras proteins or vice versa on Rho proteins reversed the differential sensitivity to Rce1 deficiency Mus musculus ?
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?

Synonyms

Synonyms Comment Organism
RCE1
-
Mus musculus