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Literature summary for 3.4.99.B1 extracted from
- Type II CAAX prenyl endopeptidases belong to a novel superfamily of putative membrane-bound metalloproteases (2001), Trends Biochem. Sci., 26, 275-277.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| E156A | inactivation | Saccharomyces cerevisiae |
| H184A | inactivation | Saccharomyces cerevisiae |
| H186A | no inactivation | Saccharomyces cerevisiae |
| H187A | no inactivation | Saccharomyces cerevisiae |
| H284A | inactivation | Saccharomyces cerevisiae |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | probably a metallo-dependent enzyme | Saccharomyces cerevisiae |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| a-factor + H2O | Saccharomyces cerevisiae | - |
fragments of a-factor | - |
? |  |
| Ras + H2O | Saccharomyces cerevisiae | - |
fragments of Ras | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| a-factor + H2O | - |
Saccharomyces cerevisiae | fragments of a-factor | - |
? | |
| Ras + H2O | - |
Saccharomyces cerevisiae | fragments of Ras | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Ras and a-factor converting enzyme | - |
Saccharomyces cerevisiae |
| RCE1 | - |
Saccharomyces cerevisiae |
| type II CAAX protease | - |
Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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