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Literature summary for 3.4.25.2 extracted from

  • Azim, M.K.; Goehring, W.; Song, H.K.; Ramachandran, R.; Bochtler, M.; Goettig, P.
    Characterization of the HslU chaperone affinity for HslV protease. [Erratum to document cited in CA143:073777] (2005), Protein Sci., 14, 2484.
No PubMed abstract available
Search for more literature for 3.4.25.2

Inhibitors

Inhibitors Comment Organism Structure
N-acetyl-Leu-Leu-norleucinal i.e. calpain inhibitor-I, inhibits HslV Escherichia coli

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information kinetics, analysis of interaction of free and inhibited HslV with HslU Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-casein + H2O interaction via HslV intact active site Escherichia coli ?
-
 ?
additional information analysis of interaction of free and inhibited HslV with HslU showing moderate affinity, scheme of substrate-induced HslUV assemblage, overview Escherichia coli ?
-
 ?
N-carbobenzyloxy-Gly-Gly-Leu-7-amido-4-methylcoumarin + H2O
-
 Escherichia coli N-carbobenzyloxy-Gly-Gly-Leu + 7-amino-4-methylcoumarin
-
 ?
SulA-maltose binding protein-fusion protein + H2O recombinant substrate, formation of a ternary complex of HslV-HslU-substrate during reaction, molecular interaction study, interaction via HslU, not HslV Escherichia coli ?
-
 ?

Synonyms

Synonyms Comment Organism
HslU chaperone
-
 Escherichia coli
HslUV complex
-
 Escherichia coli
HslV peptidase
-
 Escherichia coli
HslV protease
-
 Escherichia coli

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Escherichia coli

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Escherichia coli

Cofactor

Cofactor Comment Organism Structure
ATP dependent on Escherichia coli