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Literature summary for 3.4.25.1 extracted from

  • Tsimokha, A.S.; Mittenberg, A.G.; Kulichkova, V.A.; Kozhukharova, I.V.; Gause, L.N.; Konstantinova, I.M.
    Changes in composition and activities of 26S proteasomes under the action of doxorubicin - apoptosis inductor of erythroleukemic K562 cells (2007), Cell Biol. Int., 31, 338-348.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
doxorubicin apoptosis inductor doxorubicin increases enzymatic activities, regulates subunit composition, and phosphorylation state of 26S proteasomes Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
K-562 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Bz-Ala-Ala-Phe-7-amido-4-methylcoumarin + H2O
-
Homo sapiens ?
-
?
Bz-DL-Arg-7-amido-4-methylcoumarin + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
26S proteasome
-
Homo sapiens