Cloned (Comment) | Organism |
---|---|
expression of GST-enzyme disintegrin domain fusion protein Escherichia coli strain BL21 | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of a GST-enzyme disintegrin domain fusion protein | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | interaction of the enzyme with integrins is inhibited by antibodies against the alphaVbeta5-domain of integrin | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | interaction of the enzyme with integrins is dependent on Ca2+ or Mn2+ | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme interacts in a RGD motif-independent manner with the alphaVbeta5-domain of integrins, e.g. on the surface of myeloma but not lymphoblastoid cells, dependent on cations Ca2+ or Mn2+ | ? | - |
? | |
proteins + H2O | Homo sapiens | - |
peptides | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme interacts in a RGD motif-independent manner with the alphaVbeta5-domain of integrins, e.g. on the surface of myeloma but not lymphoblastoid cells, dependent on cations Ca2+ or Mn2+ | Homo sapiens | ? | - |
? | |
proteins + H2O | - |
Homo sapiens | peptides | - |
? |
Synonyms | Comment | Organism |
---|---|---|
M12.209 | Merops-ID | Homo sapiens |
MDC-9 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
cell adhesion assay at | Homo sapiens |